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8-OHDG anticorps

Cet anticorps anti-8-OHDG est un anticorps Souris Monoclonal détectant 8-OHDG dans EIA, IHC (fro) et IF. Adapté pour .
N° du produit ABIN111330

Aperçu rapide pour 8-OHDG anticorps (ABIN111330)

Antigène

8-OHDG (8-Hydroxyguanosine (8-OHDG))

Hôte

  • 8
  • 1
  • 1
Souris

Clonalité

  • 8
  • 2
Monoclonal

Conjugué

  • 10
Cet anticorp 8-OHDG est non-conjugé

Application

  • 8
  • 4
  • 3
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone

15A3
  • Purification

    Protein G Chromatography.

    Immunogène

    8-Hydroxyguanosine (OH8G)-BSA and -casein conjugates.

    Isotype

    IgG2b
  • Indications d'application

    Suitable for use in ELISA and Immunohistochemistry (PLP-fixed sections) to detect themarkers of oxidative damage to DNA and RNA. May also be used on Immunoaffinity columns to isolate oxidative DNA damage adductsfrom biological fluids.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL (OD 280 nm)

    Buffer

    TBS, pH 7.4 with 0.09 % Sodium Azide as preservative.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Stock

    4 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!
  • Antigène

    8-OHDG (8-Hydroxyguanosine (8-OHDG))

    Autre désignation

    8-Hydroxy-Guanosine / 8-OHG

    Classe de substances

    Chemical

    Sujet

    8 Hydroxyguanosine (80G) is a modified base which occurs in DNA as a result of oxidative stress. 8 Hydroxy-2'deoxyguanosine (8OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels of 8OHdG have been shown to increase on exposure to ionizing radiation and tobacco smoke.Synonyms: 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxyguanine, 8-Hydroxyguanosine, 8-OFdG, 8-OHG, 8OG, 8OHG, 8OHdG
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