8-OHDG anticorps

N° du produit ABIN111330

Cet anticorps anti-8-OHDG Monoclonal Souris (Clone 15A3) (ABIN111330) détecte spécifiquement 8-OHDG dans EIA, IHC (fro) et IF.

Aperçu rapide pour 8-OHDG anticorps (ABIN111330)

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp 8-OHDG est non-conjugé

Application: Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF)

Clone: 15A3

Détail du produit anti-8-OHDG anticorps

Purification: Protein G Chromatography.

Immunogène: 8-Hydroxyguanosine (OH8G)-BSA and -casein conjugates.

Isotype: IgG2b

Information d'application

Indications d'application: Suitable for use in ELISA and Immunohistochemistry (PLP-fixed sections) to detect themarkers of oxidative damage to DNA and RNA. May also be used on Immunoaffinity columns to isolate oxidative DNA damage adductsfrom biological fluids.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL (OD 280 nm)

Buffer: TBS, pH 7.4 with 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Détails sur 8-OHDG

Antigène: 8-OHDG (8-Hydroxyguanosine (8-OHDG))

Autre désignation: 8-Hydroxy-Guanosine / 8-OHG

Classe de substances: Chemical

Sujet: 8 Hydroxyguanosine (80G) is a modified base which occurs in DNA as a result of oxidative stress. 8 Hydroxy-2'deoxyguanosine (8OHdG) has become a sensitive marker of oxidative damage in cellular DNA and has been reported to be excreted in the urine. Levels of 8OHdG have been shown to increase on exposure to ionizing radiation and tobacco smoke.Synonyms: 8-Hydroxy-2'-deoxyguanosine, 8-Hydroxyguanine, 8-Hydroxyguanosine, 8-OFdG, 8-OHG, 8OG, 8OHG, 8OHdG