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HCV NS5 anticorps (AA 2190-2300)

HCV NS5 Reactivité: Hepatitis C Virus (HCV) WB, EIA, IHC (fro) Hôte: Souris Monoclonal 7-D4 unconjugated
N° du produit ABIN111768
  • Antigène Tous les produits HCV NS5
    HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
    Épitope
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 2190-2300
    Reactivité
    • 6
    • 4
    Hepatitis C Virus (HCV)
    Hôte
    • 9
    • 1
    Souris
    Clonalité
    • 9
    • 1
    Monoclonal
    Conjugué
    • 10
    Cet anticorp HCV NS5 est non-conjugé
    Application
    • 9
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Protein G Chromatography.
    Immunogène
    Recombinant antigen (HCV) genotype 1b. Remarks:
    Clone
    7-D4
    Isotype
    IgG1
  • Indications d'application
    Suitable for use in ELISA (approx. 10e-6), Western Blot (1/1000) and Immunohistochemistry(Cryostat liver sections: 1/20).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.2 containing 0.01 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Do not freeze working dilutions
  • Antigène
    HCV NS5 (Hepatitis C Virus NS5 (HCV NS5))
    Autre désignation
    HCV NS5 (HCV NS5 Produits)
    Classe de substances
    Viral Protein
    Sujet
    HCV is classified into the genus Hepacivirus of the family Flaviviridae. Like all the members of the family, HCV is an enveloped, single-stranded, positive-sense RNA virus. Its genome (about 9600 nt) is flanked at both termini by conserved, highly structured non-translated regions (NTRs) and encodes a polyprotein precursor (about 3000 aa), which is proteolytically processed by host and viral proteases to produce the structural (core, E1, E2 and p7) and non-structural (NS2, NS3, NS4A, NS4B, NS5A and NS5B) proteins of the virus. Recently, an additional protein has been identified, whose function remains unknown. NS5A is a ~56 kDa pleiotropic protein with key roles in both viral RNA replication and modulation of the physiology of the host cellSynonyms: Hepatitis C Virus Non-structural protein NS5A
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