CEACAM5 anticorps
Aperçu rapide pour CEACAM5 anticorps (ABIN111951)
Antigène
Voir toutes CEACAM5 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- C19 is useful to detect CEA in malignant adenocarcinoma, notably in the gastro-intestinal tract. Clinical relevance is also found in breast-, lung-, prostatic-,ovarian- and other carcinomas of endodermal origin (stomach, liver, pancreas). Contrary to some other antibodies, C19 stains granulocytes in blood smears and tonsils, as well as epithelial cells.
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Purification
- Affinity chromatography.
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Isotype
- IgG1
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Indications d'application
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Suitable for Immunohistochemistry on paraffin embedded sections (0.1 μg/mL, 1/4000). Microwave pretreatment forantigen retrieval is recommended. Suggested positive control: Human colon carcinoma.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Protocole
- Protocol with formalin-fixed, paraffin-embedded sections: The whole procedure is performed at room temperature
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Restrictions
- For Research Use only
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Reconstitution
- Restore with 0.5 mL distilled water.
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Concentration
- 0.4 mg/mL
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Buffer
- PBS, pH 7.2 with 10 mg/mL bovine serum albumin (BSA) as a stabilizer and 0.01 % thimerosal as a preservative.
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Agent conservateur
- Thimerosal (Merthiolate)
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Précaution d'utilisation
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- -20 °C
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- CEACAM5 (Carcinoembryonic Antigen-Related Cell Adhesion Molecule 5 (CEACAM5))
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Autre désignation
- CD66e / CEACAM5
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Sujet
- CEA is a glycoprotein of 180 kDa m.w. It is a normal constituent of the glycocalix of embryonic endodermal epithelium and is produced mainly in the mucosa of the normal colon.Synonyms: CEA, Carcinoembryonic antigen, Carcinoembryonic antigen-related cell adhesion molecule 5, Meconium antigen 100
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ID gène
- 1048
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NCBI Accession
- NP_004354
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UniProt
- P06731
Antigène
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