CD68 anticorps (FITC)
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- Antigène Voir toutes CD68 Anticorps
- CD68 (CD68 Molecule (CD68))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp CD68 est conjugé à/à la FITC
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Application
- Flow Cytometry (FACS)
- Specificité
- CD68 antibody BM4111F recognizes the 110KD integral membrane glycoprotein CD68 (Macrosialin) predominantly expressed on the intracellular lysosomes of monocytes and macrophages and to a lesser extent by dendritic cells and peripheral blood granulocytes.
- Attributs du produit
- Absorption / Emission: 495 nm / 528 nm
- Purification
- Protein A Chromatography
- Immunogène
- Cell suspensions of Human lymph node
- Clone
- Ki-M7
- Isotype
- IgG1
- Top Product
- Discover our top product CD68 Anticorps primaire
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- Indications d'application
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Flow Cytometry: Use 10 μL to label 10^6 cells in 100 μL (Membrane permeabilisation isrequired). Clone KiM7 has been reported as being also suitable for use in Immunoprecipitation andImmunohistochemistry on Frozen Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Buffer
- PBS, 0.05 % Sodium Azide, 1 % BSA
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C
- Stockage commentaire
- Store the antibody undiluted at 2-8 °C.
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- Antigène
- CD68 (CD68 Molecule (CD68))
- Autre désignation
- CD68 (CD68 Produits)
- Synonymes
- anticorps Lamp4, anticorps Scard1, anticorps gp110, anticorps GP110, anticorps LAMP4, anticorps SCARD1, anticorps CD68 molecule, anticorps CD68 antigen, anticorps Cd68 molecule, anticorps CD68, anticorps Cd68
- Sujet
- The CD68 antigen is a 37kD transmembrane protein that is post-translationally glycosylated to give a protein of 87-115kD. CD68 is specifically expressed by tissue macrophages, Langerhans cells and at low levels by dendritic cells. It could play a role in phagocytic activities of tissue macrophages, both in intracellular lysosomal metabolism and extracellular cell-cell and cell-pathogen interactions. It binds to tissue- and organ-specific lectins or selectins, allowing homing of macrophage subsets to particular sites. Rapid recirculation of CD68 from endosomes and lysosomes to the plasma membrane may allow macrophages to crawl over selectin bearing substrates or other cells. Elevated expression of CD68 has been demonstrated on CD34+ cells in various human malignancies, including several Acute Myeloid Leukaemia studies.Synonyms: Gp110, Macrophage marker, Macrosialin
- ID gène
- 968
- NCBI Accession
- NP_001035148
- UniProt
- P34810
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