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KRT8 anticorps

KRT8 Reactivité: Humain, Rat, Souris, Lapin, Mammifères WB, IF, FACS, IHC (p), IHC (fro) Hôte: Souris Monoclonal M20 unconjugated
N° du produit ABIN112173
  • Antigène Voir toutes KRT8 Anticorps
    KRT8 (Keratin 8 (KRT8))
    Reactivité
    • 247
    • 80
    • 75
    • 32
    • 31
    • 30
    • 30
    • 16
    • 14
    • 10
    • 7
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Humain, Rat, Souris, Lapin, Mammifères
    Hôte
    • 132
    • 124
    • 2
    • 1
    Souris
    Clonalité
    • 129
    • 128
    Monoclonal
    Conjugué
    • 137
    • 23
    • 17
    • 9
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    Cet anticorp KRT8 est non-conjugé
    Application
    • 163
    • 96
    • 89
    • 82
    • 67
    • 49
    • 41
    • 40
    • 32
    • 29
    • 22
    • 18
    • 5
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    M20 reacts with glandular epithelial cells (endocrine and exocrine) as well as mesothelial cells of the digestive, respiratory and urogenital tract and most adenocarcinomas derived from these cells. The M20 epitope has been mapped to amino acids 353-367 on the alpha helical rod domain of Cytokeratin 8 (See Reference 10).
    Purification
    Purified
    Immunogène
    Keratin isolated from the Human breast carcinoma cell line MCF-7
    Clone
    M20
    Isotype
    IgG1
    Top Product
    Discover our top product KRT8 Anticorps primaire
  • Indications d'application
    Immunoblotting: 1/100-1/1000Immunocytochemistry. Flow Cytometry. Immunohistochemistry on Frozen Tissues: 1/100-1/200 with Avidin-biotinylatedHorseradish peroxidase complex ABC as detection reagent.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    PBS, 0.09 % Sodium Azide
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the lyophilized antibody at 2-8 °C for one month or (in aliquots) at -20 °C for longer. When reconstituted the antibody is stable for one month at 2-8 °C.
  • Antigène
    KRT8 (Keratin 8 (KRT8))
    Autre désignation
    Cytokeratin 8 (KRT8 Produits)
    Synonymes
    anticorps CARD2, anticorps CK-8, anticorps CK8, anticorps CYK8, anticorps K2C8, anticorps K8, anticorps KO, anticorps AA960620, anticorps AL022697, anticorps AU019895, anticorps Card2, anticorps EndoA, anticorps Krt-2.8, anticorps Krt2-8, anticorps CYKER, anticorps KRT2-8, anticorps KERATIN8, anticorps ck8, anticorps cyk8, anticorps k2c8, anticorps card2, anticorps krt2-5, anticorps MGC69490, anticorps KRT8, anticorps DreK8, anticorps cb186, anticorps krt2-8, anticorps sb:cb186, anticorps wu:fa20h05, anticorps wu:fa95h10, anticorps wu:fb96c06, anticorps zf-K8, anticorps zfk8, anticorps DKFZp468F2127, anticorps keratin 8, anticorps keratin 8 S homeolog, anticorps KRT8, anticorps Krt8, anticorps krt8.S, anticorps krt8
    Sujet
    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9-7.8. The individual cytokeratin polypeptides are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8
    ID gène
    3856
    NCBI Accession
    NP_002264
    UniProt
    P05787
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