LRPAP1 anticorps

N° du produit ABIN112189

Cet anticorps Souris Monoclonal détecte spécifiquement LRPAP1 dans WB, IF et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LRPAP1 anticorps (ABIN112189)

Antigène: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LRPAP1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: 7F1

Détail du produit anti-LRPAP1 anticorps

Specificité: This antibody BM5054 (7F1) reacts with the 39 kDa RAP protein, which is cosynthesized with Human LRP/alpha2MR (low density lipoprotein receptor-related protein/alpha2-Macro-Globulin Receptor). It inhibits the binding of ligands, e.g. tPA, uPA, VLDL, liproprotein lipase, and alpha2-Macroglobulin-proteinase complexes to LRP/A2MR.

Purification: Affinity Chromatography on Protein A .

Immunogène: Human RAP.

Isotype: IgG1

Information d'application

Indications d'application: Immunoblotting. Immunofluorescence. Immunohistochemistry: 1/20. Ligand-binding assays.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in 1 mL distilled water.

Buffer: PBS buffer, pH 7.4 containing 0.5 % BSA as stabilizer.

Conseil sur la manipulation: This product is photosensitive and should be protected from light

Stock: 4 °C

Stockage commentaire: Prior to and following reconstitution store the antibody undiluted at 2-8 °C. DO NOT FREEZE!

Détails sur LRPAP1

Antigène: LRPAP1 (Low Density Lipoprotein Receptor-Related Protein Associated Protein 1 (LRPAP1))

Autre désignation: LRPAP1 / A2MRAP

Sujet: Low density lipoprotein receptor-related protein-associated protein 1 (RAP) interacts with LRP1/alpha-2-macroglobulin receptor and glycoprotein 330. It is present on the cell surface forming a complex with the alpha 2 macroglobulin receptor heavy and light chains. Binds LRP1B, binding is followed by internalization and degradation. In complex with the alpha 2 MR or gp330, it may have some role in the pathogenesis of membrane glomerular nephritis.Synonyms: Alpha-2-MRAP, Alpha-2-macroglobulin receptor-associated protein, Low density lipoprotein receptor-related protein-associated protein 1, RAP

ID gène: 4043

NCBI Accession: NP_002328

UniProt: P30533