KRT8 anticorps
Aperçu rapide pour KRT8 anticorps (ABIN112350)
Antigène
Voir toutes KRT8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This Monoclonal antibody H1 reacts with glandular epithelial cells (endocrine and exocrine) as well as mesothelial cells of the digestive, respiratory and urogenital tract and most adenocarcinomas derived from these cells.
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Réactivité croisée (Details)
- Species reactivity (tested):Human, Zebrafish.
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Purification
- Purified
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Immunogène
- Cytoskeleton preparation containing Cytokeratin 8.
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Isotype
- IgG1
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Indications d'application
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Suitable for Immunoblotting, Immunocytochemistry, immunohistochemistry on frozen andparaffin-embedded tissues and flow cytometry. Recommended dilutions: 1/25-1/200 for flow cytometry, and for immunohistochemistry with avidin-biotinylatedhorseradish peroxidase complex (ABC) as detection reagent.1/100-1/1000 for Immunoblotting applications.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.0 mg/mL
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Buffer
- PBS, 0.09 % Sodium Azide
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing. Do not freeze working dilutions.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the original vial at 2-8 °C. After reconstitution store (in aliquots) at -20 °C.
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- KRT8 (Keratin 8 (KRT8))
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Autre désignation
- Cytokeratin 8
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Sujet
- Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK8, CYK8, Cytokeratin endo A, Cytokeratin-8, K8, KRT8, Keratin, Keratin-8, type II cytoskeletal 8
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ID gène
- 3856
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NCBI Accession
- NP_002264
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UniProt
- P05787
Antigène
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