ENO1 anticorps

N° du produit ABIN112663

Cet anticorps Lapin Polyclonal détecte spécifiquement ENO1 dans WB, IHC (p), EIA et IHC (fro). Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour ENO1 anticorps (ABIN112663)

Antigène: ENO1 (Enolase 1 (ENO1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ENO1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-ENO1 anticorps

Specificité: This antibody detects Human Non-Neuronal Enolase, and demostrates less than 0.1 % cross-reactivity with non-specific Enolase.

Purification: Affinity Chromatography on Protein G

Immunogène: Native Human NNE.

Information d'application

Indications d'application: Immunohistochemistry on Frozen and Paraffin Sections (each 1/25-1/100). ELISA. Western blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 5.0 mg/mL (by OD 280 nm)

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ENO1

Antigène: ENO1 (Enolase 1 (ENO1))

Autre désignation: alpha-Enolase (ENO1)

Sujet: Non Neuronal Enolase (ENO1) is an isoform of mammalian enolase and is composed of 2 alpha subunits. The gene for ENO1 encodes alpha-enolase, a homodimeric soluble enzyme, and also encodes a shorter monomeric structural lens protein, tau-crystallin. The two proteins are made from the same message. The full length protein, the isoenzyme, is found in the cytoplasm. The shorter protein is produced from an alternative translation start, is localized to the nucleus, and has been found to bind to an element in the c-myc promoter. Non Neuronal Enolase can be as a diagnostic marker for many tumors, as a marker for endometriosis and in the heterodimeric form, alpha/gamma, as a marker for hypoxic brain injury after cardiac arrest. It has been identified as an autoantigen in Hashimoto encephalopathy (associated with Hashimoto thyroiditis).Synonyms: 2-phospho-D-glycerate hydro-lyase, C-myc promoter-binding protein, ENO1L1 Non-neural enolase, Enolase 1, MBP-1, MBPB1, MPB-1, MPB1, NNE, Phosphopyruvate hydratase, Plasminogen-binding protein

ID gène: 2023

NCBI Accession: NP_001188412

UniProt: P06733