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Tetanus Toxin anticorps (AA 1300-1314)

Cet anticorps Lapin Polyclonal détecte spécifiquement Tetanus Toxin dans EIA. Il présente une réactivité envers Clostridium tetani.
N° du produit ABIN112840

Aperçu rapide pour Tetanus Toxin anticorps (AA 1300-1314) (ABIN112840)

Antigène

Voir toutes Tetanus Toxin (TetX) Anticorps
Tetanus Toxin (TetX)

Reactivité

Clostridium tetani

Hôte

  • 7
  • 4
  • 3
Lapin

Clonalité

  • 9
  • 4
Polyclonal

Conjugué

  • 14
Cet anticorp Tetanus Toxin est non-conjugé

Application

  • 6
  • 6
  • 4
  • 2
  • 2
  • 1
  • 1
Enzyme Immunoassay (EIA)
  • Épitope

    • 2
    • 1
    AA 1300-1314

    Specificité

    This antibody detects Tetanus Toxin.

    Purification

    Affinity Chromatography on Protein A.

    Immunogène

    Synthetic peptide corresponding to the amino acids 1300-1314 of the native molecule conjugated to Keyhole limpet Haemocyanin.
  • Indications d'application

    ELISA.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    1.1 mg/mL

    Buffer

    PBS, pH 7.2 containing 0.09 % Sodium Azide as preservative.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    Tetanus Toxin (TetX)

    Autre désignation

    Tetanus Toxin

    Classe de substances

    Bacteria

    Sujet

    Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the 76-Gln-|-Phe-77 bond of synaptobrevin-2. The precursor polypeptide is subsequently cleaved to yield subchains L and H. These remain linked by a disulfide bridge and are non-toxic after separation.Synonyms: Clostridium tetani toxin, tetX

    ID gène

    1061100

    NCBI Accession

    NP_783831

    UniProt

    P04958
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