CX3CR1 anticorps (N-Term)

N° du produit ABIN113101

Cet anticorps Lapin Polyclonal détecte spécifiquement CX3CR1 dans WB, FACS et IHC (fro). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour CX3CR1 anticorps (N-Term) (ABIN113101)

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CX3CR1 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CX3CR1 anticorps

Épitope: AA 2-21, N-Term

Specificité: The antibody recognizes CX3CR1, N-terminal V28

Réactivité croisée (Details): Species reactivity (tested):Human, Mouse and Rat.

Purification: Immunoaffinity Chromatography.

Immunogène: Peptide corresponding to amino acids 2-21 of Human CX3CR1 Remarks: The sequence differs from those of Mouse and Rat CX3CR1 by four amino acids (3, 4).

Information d'application

Indications d'application: Immunohistochemistry (2 μg/mL). Flow Cytometry. Western blot (1/500-1/2,000). Human spleen tissue lysate can be used as positive control and approx. 50 kDa band can bedetected.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS with 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur CX3CR1

Antigène: CX3CR1 (Chemokine (C-X3-C Motif) Receptor 1 (CX3CR1))

Autre désignation: CX3CR1 / GPR13

Sujet: CX3CR1 is one of the chemokine receptors that are required as co-receptors for HIV infection. The genes encoding Human, Mouse, and Rat CX3CR1 were cloned and designated V28 and CMKBRL1, CX3CR1, and RBS11, respectively. The encoded seven transmembrane protein was recently identified as the receptor for a novel transmembrane molecule, fractalkine, and renamed CX3CR1. Recently, CX3CR1 was found to serve as a co-receptor for HIV-1 and HIV-2 envelope fusion and virus infection, which can be inhibited by fractokine. CX3CR1 mediates leukocyte migration and adhesion and has been implicated in tumor metastasis. CX3CR1 is expressed in a variety of human tissues and cell lines.Synonyms: Beta chemokine receptor-like 1, C-X3-C CKR-1, CMK-BRL-1, CMKBRL1, CX3C chemokine receptor 1, Fractalkine receptor, G-protein coupled receptor 13, V28

ID gène: 1524

NCBI Accession: NP_001164642

UniProt: P49238

Pathways: Cellular Response to Molecule of Bacterial Origin