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Keratin 10 anticorps

Cet anticorps anti-Keratin 10 est un anticorps Souris Monoclonal détectant Keratin 10 dans WB, FACS, IF, IHC (p) et IHC (fro). Adapté pour Humain, Chien et Cat.
N° du produit ABIN114447

Aperçu rapide pour Keratin 10 anticorps (ABIN114447)

Antigène

Voir toutes Keratin 10 (KRT10) Anticorps
Keratin 10 (KRT10)

Reactivité

  • 173
  • 88
  • 58
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  • 37
  • 5
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  • 2
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Humain, Chien, Cat

Hôte

  • 97
  • 80
  • 2
Souris

Clonalité

  • 119
  • 60
Monoclonal

Conjugué

  • 83
  • 14
  • 7
  • 7
  • 7
  • 7
  • 7
  • 7
  • 6
  • 4
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  • 2
  • 2
  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
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  • 1
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  • 1
Cet anticorp Keratin 10 est non-conjugé

Application

  • 109
  • 76
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Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone

DE-K10
  • Specificité

    DE-K10 reacts exclusively with cytokeratin 10 which is present in keratinizing stratified epithelia and in differentiated areas of highly differentiated squamous cell carcinomas.

    Purification

    Purified

    Immunogène

    Cytoskeletal preparation extracted from human epidermis.

    Isotype

    IgG1
  • Indications d'application

    Immunoblotting (1/100-1/1000). Immunocytochemistry. Immunohistochemistry on frozen sections and paraffin-embedded tissues (1/100-1/200 forImmunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) asdetection reagent). Flow cytometry (1/100-1/200).
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    1.0 mg/mL

    Buffer

    PBS, 0.09 % Sodium Azide

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    -20 °C

    Stockage commentaire

    Store lyophilized antibody at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for up to two weeks. For longer storage aliquot and store frozen at -20 °C to -80 °C.
  • Antigène

    Keratin 10 (KRT10)

    Autre désignation

    Cytokeratin 10

    Sujet

    Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The individual human cytokeratins are numbered 1 to 20. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Synonyms: CK-10, CK10, Cytokeratin-10, K10, KPP, KRT10, Keratin, Keratin-10, Type I Cytoskeletal 10

    ID gène

    3858

    NCBI Accession

    NP_000412

    UniProt

    P13645
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