CRP anticorps

N° du produit ABIN114518

L’anticorps anti-CRP Monoclonal Souris est utilisé pour la détection de CRP dans des échantillons de Humain. Il a été validé pour WB, EIA et ELISA (Capture).

Aperçu rapide pour CRP anticorps (ABIN114518)

Antigène: CRP (C-Reactive Protein (CRP))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CRP est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), ELISA (Capture)

Clone: 63F4

Détail du produit anti-CRP anticorps

Specificité: Recognizes Human CRP. No detectable cross-reaction with Human normal serum proteins. Other species not tested.

Purification: Affinity Chromatography on Protein G

Immunogène: Purified CRP from Human pleural fluid

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Immunoblot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with Double distillated water is recommended and to adjust the final concentration to 1.0 mg/mL

Concentration: 1.0 mg/mL

Buffer: 0.01 M PBS, pH 7.2

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Prior to reconstitution store at 2-8 °C. Following reconstitution store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CRP

Antigène: CRP (C-Reactive Protein (CRP))

Sujet: C Reactive Protein is a major acute phase reactant synthesized primarily in the liver hepatocytes. It is a pentraxin (cyclic pentameric protein) compound of five identical nonglycosylated subunits of 206 amino acids each (m.w. 24 kDa), that are bound noncovalently to form the physiologic CRP molecule (m.w. 117.5 kDa). C Reactive Protein mediates activities associated with preimmune nonspecific host resistance. It is opsonic, an initiator of the classical complement cascade and an activator of monocytes/macrophages. CRP also binds to several nuclear components including chromatin, histones and snRNP, suggesting that it may play a role as a scavenger during cell necrosis. Studies have revealed that among other markers of inflammation, CRP shows the strongest association with cardiovascular events. Many clinical studies demonstrated that coronary mortality among patients with unstable angina and elevated CRP is significantly higher comparing with the patients without elevated CRP. Measurements of C reactive protein (hsCRP) in the patients with ischemic heart disease provide a novel method for detecting individuals at high risk of plaque rupture.Synonyms: C Reactive Protein, PTX1, Pentraxin-related

ID gène: 1401

NCBI Accession: NP_000558

UniProt: P02741

Pathways: Carbohydrate Homeostasis