Cytokeratin 19 anticorps

N° du produit ABIN114673

Cet anticorps Souris Monoclonal détecte spécifiquement Cytokeratin 19 dans WB, IF, FACS, IHC (p) et IHC (fro). Il présente une réactivité envers Humain et Poisson zèbre (Danio rerio).

Aperçu rapide pour Cytokeratin 19 anticorps (ABIN114673)

Antigène: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Reactivité: Humain, Poisson zèbre (Danio rerio)

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Cytokeratin 19 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: RCK108

Détail du produit anti-Cytokeratin 19 anticorps

Specificité: Clone RCK108 specifically reacts with Cytokeratin 19, found in most glandular simple type epithelia and most carcinomas. Does not react with hepatocytes and hepatocellular carcinoma.

Purification: Purified

Immunogène: Cytoskeletal preparation of Human bladder carcinoma cell line T24

Isotype: IgG1

Information d'application

Indications d'application: Immunohistochemistry- on frozen sections. - on paraffin embedded tissues (pre-treatment with pepsin or trypsin). Immunocytochemistry. Immunoblotting. Flow cytometry: 1: 100 - 1: 1000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, 0.09 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in alqiuots) at -20 °C for longer.

Détails sur Cytokeratin 19

Antigène: Cytokeratin 19 (KRT19) (Keratin 19 (KRT19))

Autre désignation: Cytokeratin 19

Sujet: Cytokeratins are a subfamily of intermediate filament proteins and are characterized by a remarkable biochemical diversity, represented in human epithelial tissues by at least 20 different polypeptides. They range in molecular weight between 40 kDa and 68 kDa and isoelectric pH between 4.9 - 7.8. The various epithelia in the human body usually express cytokeratins which are not only characteristic of the type of epithelium, but also related to the degree of maturation or differentiation within an epithelium. Cytokeratin subtype expression patterns are used to an increasing extent in the distinction of different types of epithelial malignancies. The cytokeratin antibodies are not only of assistance in the differential diagnosis of tumors using immunohistochemistry on tissue sections, but are also a useful tool in cytopathology and flow cytometric assays.Individual human cytokeratins are numbered 1 to 20.Synonyms: CK19, Cytokeratin-19, K19, KRT19, Keratin type I cytoskeletal 19, Keratin-19

ID gène: 3880

NCBI Accession: NP_002267

UniProt: P08727