EpCAM anticorps

N° du produit ABIN114701

L’anticorps Souris Monoclonal anti-EpCAM a été validé pour WB et EIA. Il convient pour détecter EpCAM dans des échantillons de Humain.

Aperçu rapide pour EpCAM anticorps (ABIN114701)

Antigène: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EpCAM est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Clone: MK-1-25

Détail du produit anti-EpCAM anticorps

Specificité: The anti human EPCAM antibody, clone MK-1-25 is a mouse monoclonal antibody against recombinant human EPCAM.

Purification: Purified

Immunogène: Recombinant human EPCAM produced in E.coli

Isotype: IgG1

Information d'application

Indications d'application: ELISA. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 0.1 mL of deionized water

Concentration: 1.0 mg/mL

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE

Agent conservateur: Azide free

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 2-8 °C for up to one month. For longer storage, aliquot and freeze unused portion at -20 °C in volumes appropriate for single usage. Avoid freeze/thaw cycles.

Détails sur EpCAM

Antigène: EpCAM (EPCAM) (Epithelial Cell Adhesion Molecule (EPCAM))

Autre désignation: CD326 / EPCAM / TACSTD1

Sujet: The Ep-CAM antigen (Epithelial Cell Adhesion Molecule), also termed as MK-1, GA733-2, KSA, 17-1A or EGP40, is a 40 kDa type-I transmembrane glycoprotein with properties of Ca2+ -independent homotypic intracellular adhesion molecule. The full leghth of the molecule is 314 amino acids. Structurally, Ep-CAM is not related to any of the major families of adhesion molecules. The Ep-CAM antigen is overexpessed on the majority of tumor cells of most human epithelia of variety of tumor tissues such as stomach, colon, pancreas, gall bladder, bile duct, mammary gland, breast and lung carcinoma. Ep-CAM has been suggested to be involved in the differentiation and growth of epithelial cells under normal physiological conditions through its homotypic cell-cell adhesion activity. As it is overexpressed on most carcinomas, Ep-CAM antigen has been used as a target for diagnosis and therapy of cancer.Synonyms: Adenocarcinoma-associated antigen, EGP314, Ep-CAM, Epithelial cell adhesion molecule, Epithelial glycoprotein 314, GA733-2, KS 1/4 antigen, KSA, M1S2, M4S1, MIC18, Major gastrointestinal tumor-associated protein GA733-2, TROP1, Trop-1, Tumor-associated calcium signal transducer 1

ID gène: 4072

NCBI Accession: NP_002345

UniProt: P16422