ACP5 anticorps

N° du produit ABIN114707

L’anticorps Souris Monoclonal anti-ACP5 a été validé pour EIA. Il convient pour détecter ACP5 dans des échantillons de Humain.

Aperçu rapide pour ACP5 anticorps (ABIN114707)

Antigène: ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp ACP5 est non-conjugé

Application: Enzyme Immunoassay (EIA)

Clone: TRAP-01

Détail du produit anti-ACP5 anticorps

Specificité: The Anti Human TRAP 5 Antibody, Clone: TRAP-01 is a mouse monoclonal antibody against TRAP 5.

Purification: Affinity chromatography on protein G

Immunogène: Recombinant human TRAP 5 expressed in Sf 9 cells.

Isotype: IgG1

Information d'application

Indications d'application: Enzyme Immunoassay.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore with 1 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.

Concentration: 1.0 mg/mL

Buffer: 0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2. AZIDE FREE, None

Agent conservateur: Azide free

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: Prior to reconstitution store at -70 °C. Following reconstitution store the antibody (in aliquots) at -20 °C for 6 month.

Date de péremption: 6 months

Détails sur ACP5

Antigène: ACP5 (Acid Phosphatase 5, Tartrate Resistant (ACP5))

Autre désignation: ACP5 / TR-AP

Sujet: TRAP 5 (serum band 5 tartrate-resistant acid phosphatase, TRACP 5, EC 3.1.3.2) is a glycoprotein of 35-37 kDa. TRAP 5 belongs to the most abundant enzymes in osteoclasts. It is expressed in certain differentiated cells of the mononuclear phagocyte system, particularly osteoclasts and alveolar macrophages, where it takes an active part in bone resorption process. High blood levels of TRAP 5 are usually associated with active bone remodelling. Increased serum levels are observed during normal bone growth among healthy children. Elevated serum TRAP levels have been detected in diseases characterized by increased bone resorption, Pagets disease of the bone, hemodialysis, primary hyperparathyroidism, metastatic malignancies involving bone resorption, multiple myeloma and bilaterally ovariectomized women. Post-menopausal women have higher levels of serum than post-menopausal women on estrogen replacement therapy. Therefore specific determination of TRAP 5 activity can be essential for clinical assessment of bone metabolism.Synonyms: Acid phosphatase 5 tartrate resistant, TRAP5, TRAcP, Tartrate-resistant acid ATPase, Tartrate-resistant acid phosphatase type 5

ID gène: 54

NCBI Accession: NP_001104504

UniProt: P13686

Pathways: Transition Metal Ion Homeostasis