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Ezrin anticorps (AA 362-585)

EZR Reactivité: Humain, Souris, Rat, Boeuf (Vache), Hamster, Kangourou WB, IHC (p), IP Hôte: Souris Monoclonal 3C12 unconjugated
N° du produit ABIN115202
  • Antigène Voir toutes Ezrin (EZR) Anticorps
    Ezrin (EZR)
    Épitope
    • 30
    • 16
    • 12
    • 11
    • 9
    • 9
    • 9
    • 8
    • 5
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 362-585
    Reactivité
    • 157
    • 81
    • 74
    • 7
    • 7
    • 7
    • 6
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Humain, Souris, Rat, Boeuf (Vache), Hamster, Kangourou
    Hôte
    • 142
    • 14
    • 3
    • 2
    Souris
    Clonalité
    • 138
    • 22
    Monoclonal
    Conjugué
    • 92
    • 8
    • 8
    • 7
    • 7
    • 7
    • 7
    • 7
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Cet anticorp Ezrin est non-conjugé
    Application
    • 120
    • 54
    • 28
    • 16
    • 16
    • 15
    • 13
    • 13
    • 11
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    Specificité
    This antibody reacts with a protein of 81 kDa.
    Cellular Localization: Cell membrane
    Purification
    Purified
    Immunogène
    BALB/C mice were immunized with a recombinant fragment of human ezrin corresponding to amino acid 362-585.
    Clone
    3C12
    Isotype
    IgG1
    Top Product
    Discover our top product EZR Anticorps primaire
  • Indications d'application
    Immunoprecipitation. Western blot: 1: 100-750. Immunohistochemistry on paraffin embedded sections: dilute 1: 50-1: 100 in an ABC method(30 minutes at room temperature). Recommended positive control: Lung.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Hatano, Akiyama, Tamura, Hosogi, Marunaka, Caplan, Ueno, Tsukita, Asano: "Knockdown of ezrin causes intrahepatic cholestasis by the dysregulation of bile fluidity in the bile duct epithelium in mice." dans: Hepatology (Baltimore, Md.), Vol. 61, Issue 5, pp. 1660-71, (2015) (PubMed).

    van Steensel, Paridaens, van Meurs, van Hagen, van den Bosch, Kuijpers, Drexhage, Hooijkaas, Dik: "Orbit-infiltrating mast cells, monocytes, and macrophages produce PDGF isoforms that orchestrate orbital fibroblast activation in Graves' ophthalmopathy." dans: The Journal of clinical endocrinology and metabolism, Vol. 97, Issue 3, pp. E400-8, (2012) (PubMed).

    Fonseca, Freund, Bornhäuser, Corbeil: "Polarization and migration of hematopoietic stem and progenitor cells rely on the RhoA/ROCK I pathway and an active reorganization of the microtubule network." dans: The Journal of biological chemistry, Vol. 285, Issue 41, pp. 31661-71, (2010) (PubMed).

    Gouas, Shi, Hautefeuille, Ortiz-Cuaran, Legros, Szymanska, Galy, Egevad, Abedi-Ardekani, Wiman, Hantz, Caron de Fromentel, Chemin, Hainaut: "Effects of the TP53 p.R249S mutant on proliferation and clonogenic properties in human hepatocellular carcinoma cell lines: interaction with hepatitis B virus X protein." dans: Carcinogenesis, Vol. 31, Issue 8, pp. 1475-82, (2010) (PubMed).

    Asari, Kanemitsu, Kurihara: "Oral administration of high molecular weight hyaluronan (900 kDa) controls immune system via Toll-like receptor 4 in the intestinal epithelium." dans: The Journal of biological chemistry, Vol. 285, Issue 32, pp. 24751-8, (2010) (PubMed).

    Geissler, Dashkevich, Fischer, Fries, Kuhn-Régnier, Addicks, Mehlhorn, Bloch: "First year changes of myocardial lymphatic endothelial markers in heart transplant recipients." dans: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, Vol. 29, Issue 5, pp. 767-71, (2006) (PubMed).

  • Antigène
    Ezrin (EZR)
    Autre désignation
    Ezrin (EZR Produits)
    Synonymes
    anticorps CVIL, anticorps CVL, anticorps VIL2, anticorps ezr, anticorps vil2, anticorps wu:fc05c03, anticorps wu:fj31d06, anticorps cvil, anticorps cvl, anticorps Vil2, anticorps AW146364, anticorps R75297, anticorps p81, anticorps ezr.S, anticorps ezrin, anticorps ezrin b, anticorps ezrin L homeolog, anticorps EZR, anticorps ezrb, anticorps ezr, anticorps Ezr, anticorps ezr.L
    Sujet
    Ezrin serves as a tyrosine kinase substrate and is phosphorylated in EGF-stimulated cells. Ezrin is a cytoplasmic protein enriched in microvilli and other cell surfaces. Ezrin has an actin-binding capacity. Ezrin is expressed in epithelial cells but not in mesenchymal cells. Ezrin is also expressed by certain epithelial tumors, such as renal cell adenocarcinomas.Synonyms: Cytovillin, EZR, VIL2, Villin-2, p81
    ID gène
    7430
    NCBI Accession
    NP_001104547
    UniProt
    P15311
    Pathways
    Maintenance of Protein Location
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