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MSTN anticorps

Cet anticorps Poulet Polyclonal détecte spécifiquement MSTN dans EIA. Il présente une réactivité envers Humain.
N° du produit ABIN115510

Aperçu rapide pour MSTN anticorps (ABIN115510)

Antigène

Voir toutes MSTN Anticorps
MSTN (Myostatin (MSTN))

Reactivité

  • 86
  • 56
  • 51
  • 20
  • 9
  • 4
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Humain

Hôte

  • 98
  • 22
  • 4
  • 3
  • 2
  • 1
  • 1
Poulet

Clonalité

  • 106
  • 25
Polyclonal

Conjugué

  • 59
  • 21
  • 9
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
Cet anticorp MSTN est non-conjugé

Application

  • 101
  • 50
  • 39
  • 26
  • 26
  • 21
  • 21
  • 12
  • 8
  • 6
  • 5
  • 4
  • 4
  • 1
  • 1
Enzyme Immunoassay (EIA)
  • Séquence

    Total 248 AA. MW: 28 kDa (calculated ). 243 AA of recombinan t human Myostatin Propeptide and 5 extra AA: MGNENSEQKE NVEKEGLCNA CTWRQNTKSS RIEAIKIQIL SKLRLETAPN ISKDVIRQLL PKAPPLRELI DQYDVQRDDS SDGSLEDDDY HATTETIITM PTESDFLMQV DGKPKCCFFK FSSKIQYNKV VKAQLWIYLR PVETPTTVFV QILRLIKPMK DGTRYTGIRS LKLDMNPGTG IWQSIDVKTV LQNWLKQPES NLGIEIKALD ENGHDLAVTF PGPGEDGLNP FLEVKVTDTP KRSRRKLN Remarks: The amino acid sequence of the recombinan t Human Myostatin Propeptide is 100% homologous with the amino acid sequence of the Human Myostatin Propeptide without signaling sequence.

    Specificité

    The recombinant human myostatin propeptide is 100 % homologous with the human serum myostatin propeptide.

    Purification

    Immunoaffinity chromatography.

    Immunogène

    Recombinant human myostatin propeptide from E. coli.
  • Indications d'application

    Suitable for ELISA: Titer is defined by indirect ELISA, it is: > 1/100,000 for antibodyconcentration 1 mg/mL, 25 ng of antigen are coated per well, and is then defined at a pointof maximal decrease of the titration curve.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Add 0.05 mL of deionized water and let the lyophilized pellet dissolve completely. Slight turbidity may occur after reconstitution, which does not affect activity of the antibody. In this case clarify the solution by centrifugation.

    Concentration

    1.0 mg/mL

    Buffer

    0.05 M phosphate buffer, 0.1 M NaCl, pH 7.2 containing no preservatives.

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Avoid repeated freezing and thawing. Dilute only prior to immediate use.

    Stock

    -20 °C

    Stockage commentaire

    Store (in aliquots) at -20° C or below.
  • Antigène

    MSTN (Myostatin (MSTN))

    Autre désignation

    Myostatin

    Sujet

    Myostatin (GDF-8), a member of the TGFbeta superfamily, is a potent and specific negative regulator of skeletal muscle mass. In serum, myostatin circulates as part of a latent complex containing myostatin propeptide and/or follistatin-related gene. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70 % ) of myostatin in serum bound to its propeptide. The myostatin propeptide is negative regulator of myostatin in vivo.Synonyms: GDF-8, GDF8, Growth differentiation factor 8, MSTN

    ID gène

    2660

    NCBI Accession

    NP_005250

    UniProt

    O14793
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