PROX1 anticorps (C-Term)
Aperçu rapide pour PROX1 anticorps (C-Term) (ABIN115694)
Antigène
Voir toutes PROX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- C-Term
-
Specificité
- This antibody detects Prox-1 in the nucleus of lymphatic endothelial cells.
-
Réactivité croisée (Details)
-
Species reactivity (expected):Rat.
Species reactivity (tested):Human, Mouse. -
Purification
- Protein A Chromatography
-
Immunogène
- Highly pure (>95%) recombinant Human, highly conserved C-terminal part of Prox1 (homeo domain and prospero domain) derived from E.coli.
-
-
-
-
Indications d'application
-
Western blot (1 - 5 μg/mL). Immunofluorescence (1: 750 - 1: 1000). Immunohistochemistry: the antibody works well with paraffin sections. A boiling step isrecommended when staining paraffin-embedded tissues.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
-
-
-
Reconstitution
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
-
Buffer
- 5 mM PBS, pH 7.4 without stabilizer or preservative
-
Agent conservateur
- Without preservative
-
Conseil sur la manipulation
- Avoid repeated freezing and thawing.
-
Stock
- 4 °C/-20 °C
-
Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
-
-
- PROX1 (Prospero Homeobox 1 (PROX1))
-
Autre désignation
- PROX-1
-
Sujet
- Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lympathic vessels from blood vessels. Prox1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1
-
ID gène
- 5629
-
NCBI Accession
- NP_002754
-
UniProt
- Q92786
-
Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
Antigène
-