PROX1 anticorps (C-Term)
Aperçu rapide pour PROX1 anticorps (C-Term) (ABIN115695)
Antigène
Voir toutes PROX1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Specificité
- This antibody will detect Prox-1 in the nucleus of lymphatic endothelial cells by Immunostaining. This antibody cross reacts with Equine Prox-1 in Immunohistochemistry using Paraffin-Embedded Sections (Figure 2).
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Purification
- Antigen-Affinity Chromatography.
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Immunogène
- Recombinant Human C-terminal part of the Homeobox Transcription Factor Prox-1 (homeo domain and prospero domain).
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Indications d'application
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Immunofluorescence: Use 1/750-1/1000 dilution. Western Bloting: Use 1-5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with distilled sterile water to a concentration of 0.1-1.0 mg/mL
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Buffer
- 5 mM PBS, pH 7.2 without preservatives
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Dilute only prior to immediate use
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Stock
- 4 °C
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Stockage commentaire
- Store the antibody at 2-8 °C as an undiluted liquid. DO NOT FREEZE! Freezing alkaline phosphatase conjugates will result in a substantial loss of enzymatic activity.
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- PROX1 (Prospero Homeobox 1 (PROX1))
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Autre désignation
- PROX-1
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Sujet
- Prox-1 is a homeobox gene and acts as a master switch for lymphatic endothelial phenotype. Expression of Prox-1 in blood endothelial cells induces expression of other lymphatic marker genes. Together with Podoplanin, Prox-1 can be used to reliably distinguish lymphatic vessels from blood vessels. Prox-1 is expressed in CNS, eye, pancreas, liver and heart, and it is one of the most specific and reliable markers for lymphatic endothelial cells.Synonyms: Homeobox prospero-like protein PROX1, PROX1, Prospero homeobox protein 1
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ID gène
- 5629
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NCBI Accession
- NP_002754
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UniProt
- Q92786
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Pathways
- Stem Cell Maintenance, Regulation of Muscle Cell Differentiation
Antigène
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