CCL8 anticorps

N° du produit ABIN115779

Cet anticorps anti-CCL8 est un anticorps Souris Monoclonal détectant CCL8 dans WB, EIA et Func. Adapté pour Humain.

Aperçu rapide pour CCL8 anticorps (ABIN115779)

Antigène: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CCL8 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Détail du produit anti-CCL8 anticorps

Specificité: Reacts with Human Macrophage Chemotactic Protein-2 (MCP-2)

Purification: Affinity Chromatography on Protein A

Immunogène: Highly pure (>98%) recombinant Human MCP-2

Isotype: IgG1

Information d'application

Indications d'application: ELISA: In a sandwich ELISA (assuming 100 μL/well), a concentration of 1.0-2.0 μg/mL of thisantibody will detect at least 100 pg/mL of recombinant human MCP-2 when used withBiotin anti-Human MCP-2 antibody (cat. PP1047B) as the detection antibody at aconcentration of approximately 0.5-1.0 μg/mL. Western Blot: To detect Human MCP-2 by Western Blot analysis this antibody can be usedat a concentration of 0.25-0.50 μg/mL. Used in conjunction with compatible secondaryreagents the detection limit for recombinant hMCP-2 is 0.25-0.50 ng/lane, undernon-reducing conditions. Neutralization: To yield one-half maximal inhibition [ND50] of the biological activity ofHuman MCP-2 (100 ng/mL), a concentration of 0.8-1.0 μg/mL of this antibody is required.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 1.0 mg/mL.

Buffer: PBS without preservatives

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur CCL8

Antigène: CCL8 (Chemokine (C-C Motif) Ligand 8 (CCL8))

Autre désignation: MCP2 / CCL8

Sujet: MCP 2 (Monocyte Chemoattractant Protein 2) is a chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. MCP 2 is important to inflammatory host responses, and is found in the highest concentration in the small intestine and peripheral blood cells. This protein is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection.Synonyms: C-C motif chemokine 8, CCL-8, HC14, MCP-2, Monocyte Chemotactic Protein-2, Monocyte chemoattractant protein 2, SCYA10, SCYA8, Small-inducible cytokine A8

ID gène: 6355

NCBI Accession: NP_005614

UniProt: P80075