CCL7 anticorps
Aperçu rapide pour CCL7 anticorps (ABIN115897)
Antigène
Voir toutes CCL7 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Reacts with Macrophage Chemotactic Protein-3 (MCP-3)
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Purification
- Affinity Chromatography employing an immobilized Murine MCP-3 matrix
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Immunogène
- Highly pure (>98%) E.coli derived recombinant Murine MCP-3.
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Indications d'application
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Neutralization. ELISA: To detect mMCP-3 by direct ELISA (using 100 l/well antibody solution) a concentration ofat least 0.5 μg/mL of this antibody is required. This antigen affinity purified antibody, inconjunction with compatible secondary reagents, allows the detection of 0.2-0.4 ng/wellof recombinant mMCP-3. Western Blot: To detect mMCP-3 by Western Blot analysis this antibody can be used at a concentration of0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detection limitfor recombinant mMCP-3 is 1.5-3.0 ng/lane, under either reducing or non-reducingconditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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Buffer
- PBS, pH 7.2 without preservatives
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Prior to reconstitution store at 2-8 °C. Following reconstitution store the antibody at -20 °C.
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- CCL7 (Chemokine (C-C Motif) Ligand 7 (CCL7))
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Autre désignation
- MCP3 / CCL7
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Sujet
- This is a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix.Synonyms: C-C motif chemokine 7, CCL-7, MCP-3, Macrophage Chemotactic Protein-3, Monocyte chemoattractant protein 3, Monocyte chemotactic protein 3, NC28, SCYA6, SCYA7, Small-inducible cytokine A7
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ID gène
- 20306
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NCBI Accession
- NP_038682
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UniProt
- Q03366
Antigène
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