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Ccl21a anticorps

Cet anticorps Lapin Polyclonal détecte spécifiquement Ccl21a dans WB, EIA et Func. Il présente une réactivité envers Souris.
N° du produit ABIN115921

Aperçu rapide pour Ccl21a anticorps (ABIN115921)

Antigène

Voir toutes Ccl21a (CCL21A) Anticorps
Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

Reactivité

  • 3
  • 2
  • 1
Souris

Hôte

  • 3
Lapin

Clonalité

  • 3
Polyclonal

Conjugué

  • 2
  • 1
Cet anticorp Ccl21a est non-conjugé

Application

  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)
  • Specificité

    This antibody recognises Murine Exodus-2.

    Purification

    Affinity chromatography.

    Immunogène

    Highly pure (>98%) recombinant Mouse Exodus-2.
  • Indications d'application

    Neutralisation: To yield one-half maximal inhibition [ND50] of the biological activity of mExodus-2 (100.0 ng/mL), a concentration of 9.0-10.0 μg/mL of this antibody is required. ELISA: To detect mExodus-2 by direct ELISA (using 100 l/well antibody solution) a concentrationof at least 0.5 μg/mL of this antibody is required. This antigen affinity purified antibody, inconjunction with compatible secondary reagents, allows the detection of 0.2-0.4 ng/wellof recombinant mExodus-2. Western blot: To detect mExodus-2 by Western Blot analysis this antibody can be used at a concentrationof 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant mExodus-2 is 1.5-3.0 ng/lane, under either reducing or non-reducingconditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

    Buffer

    PBS, pH 7.2 without preservatives.

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Antigène

    Ccl21a (CCL21A) (Chemokine (C-C Motif) Ligand 21A (Serine) (CCL21A))

    Autre désignation

    6Ckine / CCL21a

    Sujet

    Exodus 2 is one of several CC cytokine genes clustered on the p arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterised by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).Synonyms: Beta chemokine exodus-2, C-C motif chemokine 21a, Scya21a, Small-inducible cytokine A21a, TCA-4, TCA4, Thymus-derived chemotactic agent 4

    ID gène

    100039131

    NCBI Accession

    NP_035465

    UniProt

    P84443
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