CXCL2 anticorps

N° du produit ABIN116031

Détail du produit anti-CXCL2 anticorps

Antigène: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL2 est non-conjugé

Application: Western Blotting (WB), Functional Studies (Func), Enzyme Immunoassay (EIA)

Specificité: This antibody detects GRO-beta.

Purification: Affinity Chromatography employing immobilized hGRO-beta matrix.

Immunogène: Highly pure (>98%) recombinant hGRO-beta (human GRO-beta)

Information d'application

Indications d'application: Neutralization(To yield one-half maximal inhibition [ND50] of the biological activity of hGRO-beta (100.00 ng/mL), a concentration of 0.5-1.0 μg/mL of this antibody has been used with previous lots)ELISA(Indirect): To detect hGRO-beta by indirect ELISA (using 100 μL/well antibody solution) aconcentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of atleast 0.2-0.4 ng/well of recombinant hGRO-beta. (Sandwich): To detect hGRO-beta by sandwich ELISA (using 100 μL/well antibody solution)a concentration of 0.5 - 2.0 μg/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with biotinylated anti-Human GRO-beta as a detection antibody,allows the detection of at least 0.2 - 0.4 ng/well of recombinant hGRO-beta. Western BlotTo detect hGRO-beta by Western Blot analysis this antibody can be used at a concentrationof 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant hGRO-beta is 1.5-3.0 ng/lane, under either reducing or non-reducing

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: The lyophilized antibody is stable at -20 °C for one year from despatch. The reconstituted antibody is stable for two weeks at 2-8 °C. Frozen aliquots are stable for six months when stored at -20 °C.

Date de péremption: 12 months

Détails sur CXCL2

Antigène: CXCL2 (Chemokine (C-X-C Motif) Ligand 2 (CXCL2))

Autre désignation: CXCL2 / MIP2A (CXCL2 Produits)

Synonymes: anticorps CINC-2a, anticorps GRO2, anticorps GROb, anticorps MGSA-b, anticorps MIP-2a, anticorps MIP2, anticorps MIP2A, anticorps SCYB2, anticorps GRO3, anticorps Gro2, anticorps MIP-2, anticorps Mgsa-b, anticorps Mip2, anticorps Scyb, anticorps Scyb2, anticorps Mip-2, anticorps GROB, anticorps MIP-2alpha, anticorps C-X-C motif chemokine ligand 2, anticorps chemokine (C-X-C motif) ligand 2, anticorps CXCL2, anticorps Cxcl2

Sujet: GRO beta is a member of the CXC, or chemokine class. It contains the ELR domain immediately preceding the first cysteine residue near the amino terminus. Other chemokines in this group include IL8, GRO alpha/beta/gamma, mouse KC, ENA78, GCP2, PBP/CTAPIII/beta TG/NAP2. These chemokines act primarily on neutrophils as chemoattractants and activators, including neutrophil degradation with release of myloperoxidase and other enzymes. GRO beta was originally identified as a heparin-binding protein secreted from a murine macrophage cell line in response to endotoxin stimulation. GRO beta is an approximately 8 kDa polypeptide of 73 amino acids. The precursor form of GRO beta consists of 100 amino acids. To generate the mature GRO beta, the precursor cleaves its amino terminal 27 amino acids. GRO beta shows 60 % amino acid homology to human GRO alpha and GRO gamma.Synonyms: C-X-C motif chemokine 2, GRO2, GROB, Gro-beta, Growth-regulated protein beta, MIP-2A, MIP2-alpha, Macrophage inflammatory protein 2-alpha, SCYB2

ID gène: 2920

NCBI Accession: NP_002080

UniProt: P19875

Pathways: Cellular Response to Molecule of Bacterial Origin