CCL1 anticorps

N° du produit ABIN116047

Détail du produit anti-CCL1 anticorps

Antigène: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCL1 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificité: This antibody reacts with human I-309.

Purification: Affinity chromatography.

Immunogène: Highly pure (>98%) recombinant hI-309.

Information d'application

Indications d'application: Neutralization. ELISA: To detect hI-309 by direct ELISA (using 100 l/well antibody solution) aconcentration of at least 0.5 μg/mL of this antibody is required. This antigen affinitypurified antibody, in conjunction with compatible secondary reagents, allows the detectionof 0.2-0.4 ng/well of recombinant hI-309. Western Blot: To detect hI-309 by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hI-309 is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur CCL1

Antigène: CCL1 (Chemokine (C-C Motif) Ligand 1 (CCL1))

Autre désignation: CCL1 / I-309 (CCL1 Produits)

Synonymes: anticorps I-309, anticorps P500, anticorps SCYA1, anticorps SISe, anticorps TCA3, anticorps BF534335, anticorps Scya1, anticorps Tca-3, anticorps CCLi6, anticorps chemokine, anticorps C-C motif chemokine ligand 1, anticorps chemokine (C-C motif) ligand 1, anticorps CCL1, anticorps Ccl1

Sujet: I-309 is a member of the C-C, or beta chemokine class. Other chemokines in this group include MIP1 alpha, MIP1 beta, RANTES, MCP1/2/3/4, mouse JE, 1 - 2 μg/mL antibody detects 20 and mouse MARC, eotaxin, HCC1 and C10. These chemokines act primarily as chemoattractants and activate monocytes, dendritic cells, T lymphocytes, natural killer cells, B lymphocytes, basophils and eosinophils. I-309 was originally identified by subtractive hybridization as a transcript that was present in a gamma/delta T cell line but not in EBVtransformed B cells. I-309 is a chemoattractant for monocytes, but not for neutrophils. IP-10 is an approximately 8.5 kD polypeptide of 73 amino acids. The precursor form of human I-309 consists of 96 amino acids. To generate the mature I-309, the precursor cleaves its hydrophobic signal peptide. Human I-309 is thought to be a homologue of the mouse TCA3, and shows 42 % amino acid homology to mouse TCA3.Synonyms: C-C motif chemokine 1, CCL-1, SCYA1, Small-inducible cytokine A1, T lymphocyte-secreted protein I-309

ID gène: 6346

NCBI Accession: NP_002972

UniProt: P22362