CXCL11 anticorps

N° du produit ABIN116297

Détail du produit anti-CXCL11 anticorps

Antigène: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CXCL11 est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA), Functional Studies (Func)

Specificité: This antibody reacts with Human I-TAC

Purification: Affinity chromatography.

Immunogène: Highly pure (>98%) recombinant hI-TAC.

Information d'application

Indications d'application: Neutralization: To yield one-half maximal inhibition [NND50] of the biological activity ofhI-TAC (100 ng/mL), a concentration of 7.0-8.0 μg/mL of this antibody is required. ELISA: To detect hI-TAC by direct ELISA (using 100l/well antibody solution) aconcentration of at least 0.5g/mL of this antibody is required. This antigen affinity purifiedantibody, in conjunction with compatible secondary reagents, allows the detection of0.2-0.4 ng/well of recombinant hI-TAC. Western Blot: To detect hI-TAC by Western Blot analysis this antibody can be used at aconcentration of 0.1-0.2 μg/mL. Used in conjunction with compatible secondary reagentsthe detection limit for recombinant hI-TAC is 1.5-3.0 ng/lane, under either reducing ornon-reducing conditions.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Reconstitution: Restore in sterile water to a concentration of 0.1-1.0 mg/mL.

Buffer: PBS, pH 7.2 without preservatives.

Agent conservateur: Without preservative

Conseil sur la manipulation: Avoid repeated freezing and thawing. Centrifuge vial prior to opening!

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.

Détails sur CXCL11

Antigène: CXCL11 (Chemokine (C-X-C Motif) Ligand 11 (CXCL11))

Autre désignation: CXCL11 / ITAC (CXCL11 Produits)

Synonymes: anticorps H174, anticorps I-TAC, anticorps IP-9, anticorps IP9, anticorps SCYB11, anticorps SCYB9B, anticorps b-R1, anticorps Cxc11, anticorps I-tac, anticorps Ip9, anticorps Itac, anticorps Scyb11, anticorps Scyb9b, anticorps betaR1, anticorps C-X-C motif chemokine ligand 11, anticorps chemokine (C-X-C motif) ligand 11, anticorps CXCL11, anticorps Cxcl11

Sujet: This member of the the intercrine alpha (chemokine CxC) family is chemotactive for interleukin-activated T cells but not unstimulated T cells, neutrophils or monocytes. It induces calcium release in activated T cells and binds to CXCR3. It may play an important role in CNS diseases which involve T cell recruitment and in skin immune responses. It is expressed at high levels in peripheral blood leukocytes, pancreas and liver astrocytes and at moderate levels in thymus, spleen and lung. It is induced by interferon gamma and interferon beta.Synonyms: Beta-R1, C-X-C motif chemokine 11, H174, I-TAC, IP-9, Interferon-gamma-inducible protein 9, Interferon-inducible T-cell alpha chemoattractant, SCYB11, SCYB9B, Small-inducible cytokine B11

ID gène: 6373

NCBI Accession: NP_005400

UniProt: O14625