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IL-22 anticorps (Biotin)

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-22 dans WB et EIA. Il présente une réactivité envers Souris.
N° du produit ABIN116491

Aperçu rapide pour IL-22 anticorps (Biotin) (ABIN116491)

Antigène

Voir toutes IL-22 (IL22) Anticorps
IL-22 (IL22) (Interleukin 22 (IL22))

Reactivité

  • 91
  • 48
  • 27
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
Souris

Hôte

  • 72
  • 21
  • 12
  • 11
  • 2
  • 1
Lapin

Clonalité

  • 81
  • 35
  • 2
Polyclonal

Conjugué

  • 65
  • 15
  • 6
  • 4
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp IL-22 est conjugé à/à la Biotin

Application

  • 78
  • 49
  • 38
  • 21
  • 13
  • 13
  • 10
  • 10
  • 9
  • 5
  • 4
  • 3
  • 3
  • 3
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Enzyme Immunoassay (EIA)
  • Specificité

    This antibody recognizes murine IL-22. Not tested in other species.

    Purification

    Affinity chromatography

    Immunogène

    Highly pure (>98%) recombinant mIL-22 (murine Interleukin-22)
  • Indications d'application

    ELISA: Direct - To detect mIL-22 by direct ELISA (using 100 l/well antibody solution) this antibodycan be used at a concentration of 0.25 - 1.0 μg/mL, allows the detection of at least 0.2 - 0.4 ng/well of recombinant mIL-22. Sandwich - To detect mIL-22 by sandwich ELISA (using 100 l/well antibody solution),a concentration of 0.25 - 1.0 μg/mL of this antibody is required. In conjunction with apolyclonal anti-murine IL-22 (PP1226P) as the capture antibody at least 0.2 - 0.4 ng/well ofrecombinant mIL-22 can be detected. Western blot: To detect mIL-22 by Western Blot analysis this antibody can be used at a concentration of0.1 - 0.2 μg/mL. Used in conjunction with compatible secondary reagents the detectionlimit for recombinant mIL-22 is 1.5 -3.0 ng/lane, under either reducing or non-reducingconditions.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Reconstitution

    Centrifuge vial prior to opening. Restore with sterile PBS solution containing 0.1 % BSA to a concentration of 0.1 - 1.0 mg/mL.

    Buffer

    BPS, pH 7.2, without preservatives

    Agent conservateur

    Without preservative

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    The lyophilized antibody is stable at -20 °C for one year from despatch. The reconstituted antibody can be stored for two weeks at 2-8 °C. Frozen aliquots are stable for six months when stored at -20 °C.

    Date de péremption

    12 months
  • Antigène

    IL-22 (IL22) (Interleukin 22 (IL22))

    Autre désignation

    Interleukin-22 / IL22

    Sujet

    IL22 is a cytokine structurally related to IL10 and is upregulated in activated T cells. IL22 signals through a receptor complex that includes CRF2-4 and a new member of the class II cytokine receptor family (also known as the interferon receptor family), IL22R. CRF2-4 has previously been demonstrated to be a functional component of the IL-10 signaling complex. IL22 is able to suppress IL4 production, this may have therapeutic potential, particularly in the treatment of asthma.Synonyms: Cytokine Zcyto18, IL-10-related T-cell-derived-inducible factor, IL-22, ILTIF

    ID gène

    50929

    NCBI Accession

    NP_058667

    UniProt

    Q9JJY9
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