RBP4 anticorps
Aperçu rapide pour RBP4 anticorps (ABIN1169044)
Antigène
Voir toutes RBP4 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- anti-RBP4 (mouse), pAb
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Specificité
- Recognizes mouse RBP4. Detects a band of ~22-25 kDa by Western blot.
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Attributs du produit
- Polyclonal Antibody. Recognizes mouse RBP4. Detects a band of ~22-25 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant mouse RBP4.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Date de péremption
- 6 months
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: "The cAMP-HMGA1-RBP4 system: a novel biochemical pathway for modulating glucose homeostasis." dans: BMC biology, Vol. 7, pp. 24, (2009) (PubMed).
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- RBP4 (Retinol Binding Protein 4, Plasma (RBP4))
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Autre désignation
- RBP4
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Sujet
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Alternate Names/Synonyms: Retinol Binding Protein 4
Product Description: Retinol binding protein 4 (RBP4, RBP) is a 21 kDa secreted protein, a member of the lipocalin family and is known as the primary transporter of retinol (vitamin A) to tissues. A recent report revealed RBP4 as an adipokine linking glucose transporter 4 (GLUT4) suppression in adipose tissue to insulin. Elevated human and mouse serum RBP4 levels are associated with insulin resistance and its severity, obesity and certain components of metabolic syndrome. Furthermore, human serum RBP4 levels are closely related to renal function.
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UniProt
- Q00724
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Pathways
- Regulatory RNA Pathways, Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis, Production of Molecular Mediator of Immune Response
Antigène
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