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SIRT6 anticorps

SIRT6 Reactivité: Humain WB, ELISA Hôte: Souris Monoclonal S6R82-2 unconjugated
N° du produit ABIN1169069
  • Antigène Voir toutes SIRT6 Anticorps
    SIRT6 (Sirtuin 6 (SIRT6))
    Reactivité
    • 91
    • 31
    • 16
    • 5
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Humain
    Hôte
    • 88
    • 11
    • 2
    Souris
    Clonalité
    • 83
    • 18
    Monoclonal
    Conjugué
    • 52
    • 12
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp SIRT6 est non-conjugé
    Application
    • 82
    • 39
    • 36
    • 14
    • 14
    • 11
    • 8
    • 7
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    Western Blotting (WB), ELISA
    Specificité
    Recognizes human sirtuin 6. Detects a band of ~47 kDa by Western blot.
     Réactivité croisée
    Humain
    Stérilité
    0.2 μm filtered
    Immunogène
    Recombinant human sirtuin 6.
    Clone
    S6R82-2
    Isotype
    IgG2b
    Top Product
    Discover our top product SIRT6 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 1 year after receipt when stored at -20°C.
    Date de péremption
    12 months
  • Antigène
    SIRT6 (Sirtuin 6 (SIRT6))
    Autre désignation
    Sirtuin 6 (SIRT6 Produits)
    Synonymes
    anticorps 2810449N18Rik, anticorps AI043036, anticorps Sir2l6, anticorps SIR2L6, anticorps zgc:86729, anticorps sirtuin 6, anticorps sirtuin 6 S homeolog, anticorps Sirt6, anticorps SIRT6, anticorps sirt6.S, anticorps sirt6
    Sujet
    Sirtuin 6 (SIRT6) is a NAD-dependent protein deacetylase with activity towards 'Lys-9' and 'Lys-56' of histone H3. It modulates acetylation of histone H3 in telomeric chromatin during the S-phase of the cell cycle. It is required for genomic stability and for normal IGF1 serum levels and normal glucose homeostasis. It also regulates cellular senescence and apoptosis. Unlike most sirtuins, SIRT6 preferentially removes long-chain fatty-acyl, rather than acetyl, protein modifications. This activity regulates secretion of the inflammation-associated protein TNF-alpha.
    UniProt
    Q8N6T7
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