SIRT6 anticorps (C-Term)
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- Antigène Voir toutes SIRT6 Anticorps
- SIRT6 (Sirtuin 6 (SIRT6))
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Épitope
- AA 290-319, C-Term
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Reactivité
- Humain, Souris
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp SIRT6 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
- Immunogène
- This SIRT6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 290-319 amino acids from the C-terminal region of human SIRT6.
- Clone
- RB2109
- Isotype
- Ig Fraction
- Top Product
- Discover our top product SIRT6 Anticorps primaire
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- Indications d'application
- WB: 1:1000. WB: 1:500. IHC-P: 1:50~100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid freeze-thaw cycles.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots.
- Date de péremption
- 6 months
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SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." dans: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).
: "Cyclic AMP Mimics the Anti-ageing Effects of Calorie Restriction by Up-Regulating Sirtuin." dans: Scientific reports, Vol. 5, pp. 12012, (2015) (PubMed).
: "Direct evidence of sirtuin downregulation in the liver of non-alcoholic fatty liver disease patients." dans: Annals of clinical and laboratory science, Vol. 44, Issue 4, pp. 410-8, (2014) (PubMed).
: "Sirtuin-3 (SIRT3), a novel potential therapeutic target for oral cancer." dans: Cancer, Vol. 117, Issue 8, pp. 1670-8, (2011) (PubMed).
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SIRT7 is a histone desuccinylase that functionally links to chromatin compaction and genome stability." dans: Nature communications, Vol. 7, pp. 12235, (2018) (PubMed).
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- Antigène
- SIRT6 (Sirtuin 6 (SIRT6))
- Autre désignation
- SIRT6 (SIRT6 Produits)
- Synonymes
- anticorps 2810449N18Rik, anticorps AI043036, anticorps Sir2l6, anticorps SIR2L6, anticorps zgc:86729, anticorps sirtuin 6, anticorps sirtuin 6 S homeolog, anticorps Sirt6, anticorps SIRT6, anticorps sirt6.S, anticorps sirt6
- Sujet
- SIRT6 is a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined, however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity.
- Poids moléculaire
- 39119
- ID gène
- 51548
- NCBI Accession
- NP_001180214, NP_057623
- UniProt
- Q8N6T7
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