LAG3 anticorps (N-Term)

N° du produit ABIN1169104

Cet anticorps Souris Monoclonal détecte spécifiquement LAG3 dans WB, IHC, IP, ICC, FACS et Func. Il présente une réactivité envers Humain.

Aperçu rapide pour LAG3 anticorps (N-Term) (ABIN1169104)

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAG3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Functional Studies (Func)

Clone: 17B4

Détail du produit anti-LAG3 anticorps

Épitope: N-Term

Specificité: Recognizes human LAG-3.

Réactivité croisée: Humain

Pureté: >95 % (SDS-PAGE)

niveau d'endotoxine: <0.001EU/μg purified protein or <1EU/mg purified protein (LAL test, Lonza).

Immunogène: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: In PBS.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur LAG3

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Autre désignation: LAG-3

Sujet: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints