LAG3 anticorps (N-Term) (FITC)
Aperçu rapide pour LAG3 anticorps (N-Term) (FITC) (ABIN1169106)
Antigène
Voir toutes LAG3 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Épitope
- N-Term
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Fonction
- anti-LAG-3 (human), mAb (17B4) (FITC)
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Specificité
- Recognizes human LAG-3.
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Attributs du produit
- Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS. Liquid. In PBS containing 0.02 % sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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Pureté
- >95 % (SDS-PAGE)
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Immunogène
- Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.
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Isotype
- IgG1 kappa
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- In PBS containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Do not freeze.Protect from light.
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Stock
- 4 °C
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Stockage commentaire
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+4°C
+4°C
Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.
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Date de péremption
- 12 months
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- LAG3 (Lymphocyte-Activation Gene 3 (LAG3))
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Autre désignation
- LAG-3
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Sujet
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Alternate Names/Synonyms: Lymphocyte Activation Gene-3, FDC Protein, CD223
Product Description: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.
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UniProt
- P18627
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
Antigène
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