LAG3 anticorps (N-Term) (Atto 488)

N° du produit ABIN1169108

L’anticorps anti-LAG3 Monoclonal Souris est utilisé pour la détection de LAG3 dans des échantillons de Humain. Il a été validé pour ICC et FACS.

Aperçu rapide pour LAG3 anticorps (N-Term) (Atto 488) (ABIN1169108)

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAG3 est conjugé à/à la Atto 488

Application: Immunocytochemistry (ICC), Flow Cytometry (FACS)

Clone: 17B4

Détail du produit anti-LAG3 anticorps (Atto 488)

Épitope: N-Term

Fonction: anti-LAG-3 (human), mAb (17B4) (ATTO 488)

Specificité: Recognizes human LAG-3.

Attributs du produit: Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: FACS, ICC. Liquid. In PBS containing 0.02 % sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

Pureté: >95 % (SDS-PAGE)

Immunogène: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

New ATTO-fluorescent antibodies show increased photostability, outstanding brightness and intense signals. ATTO dyes are thermally stable, resistant to environmental changes and show no significant isomerization. ATTO 488 shows bright green fluorescence (lambdaabs (max): 501nm, lambdaem (max): 523nm, epsilonmax: 90'000).

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Do not freeze.Protect from light.

Stock: 4 °C

Stockage commentaire:

+4°C

+4°C

Keep conjugated formats at +4°C. Stable for at least 1 year after receipt when stored at +4°C.

Date de péremption: 12 months

Détails sur LAG3

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Autre désignation: LAG-3

Sujet:

Alternate Names/Synonyms: Lymphocyte Activation Gene-3, FDC Protein, CD223

Product Description: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints