LAG3 anticorps (N-Term) (Biotin)

N° du produit ABIN1169110

Cet anticorps Souris Monoclonal détecte spécifiquement LAG3 dans ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour LAG3 anticorps (N-Term) (Biotin) (ABIN1169110)

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp LAG3 est conjugé à/à la Biotin

Application: ELISA

Clone: 17B4

Détail du produit anti-LAG3 anticorps (Biotin)

Épitope: N-Term

Fonction: anti-LAG-3 (human), mAb (17B4) (Biotin)

Specificité: Recognizes human LAG-3.

Attributs du produit: Monoclonal Antibody. Recognizes human LAG-3. Isotype: Mouse IgG1. Clone: 17B4. Applications: ELISA. Liquid. In PBS containing 0.02 % sodium azide. Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

niveau d'endotoxine: <0.001EU/μg purified protein or <1EU /mg purified protein (LAL test, Lonza).

Immunogène: Synthetic peptide corresponding to 30 aa in the N-terminus of human LAG-3.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: In PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur LAG3

Antigène: LAG3 (Lymphocyte-Activation Gene 3 (LAG3))

Autre désignation: LAG-3

Sujet:

Alternate Names/Synonyms: Lymphocyte Activation Gene-3, FDC Protein, CD223

Product Description: Lymphocyte activation gene 3 (LAG-3, CD223) plays an important role in negatively regulating T cell proliferation, function and homeostasis. It is required for maximal natural and induced regulatory T cell (Treg) function. LAG-3 is closely related to the T cell co-receptor CD4 and binds to MHC class II molecules but with a significantly higher affinity than CD4.

UniProt: P18627

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints