Cet anticorps anti-IL-37 Polyclonal Lapin (ABIN1169178) détecte spécifiquement IL-37 dans WB, IHC, ELISA et IP.
L’anticorps est réactif avec des échantillons de Humain.
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Format
Liquid
Concentration
Lot specific
Buffer
0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
Agent conservateur
Without preservative
Stock
4 °C,-20 °C
Stockage commentaire
Short Term Storage: +4°C Long Term Storage: -20°C Stable for at least 6 months after receipt when stored at -20°C.
Date de péremption
6 months
Antigène
IL-37 (IL37)
(Interleukin 37 (IL37))
Autre désignation
IL-37
Sujet
IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.