IL-37 anticorps

N° du produit ABIN1169178

Détail du produit anti-IL-37 anticorps

Antigène: IL-37 (IL37) (Interleukin 37 (IL37))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-37 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunoprecipitation (IP)

Specificité: Recognizes human IL-37. Detects a band of ~30 kDa by Western blot.

Réactivité croisée: Humain

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human IL-37.

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C.

Date de péremption: 6 months

Détails sur IL-37

Antigène: IL-37 (IL37) (Interleukin 37 (IL37))

Autre désignation: IL-37 (IL37 Produits)

Synonymes: anticorps FIL1, anticorps FIL1(ZETA), anticorps FIL1Z, anticorps IL-1F7, anticorps IL-1H, anticorps IL-1H4, anticorps IL-1RP1, anticorps IL-37, anticorps IL1F7, anticorps IL1H4, anticorps IL1RP1, anticorps interleukin 37, anticorps IL37

Sujet: IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.

UniProt: Q9NZH6