IL-37 anticorps
Aperçu rapide pour IL-37 anticorps (ABIN1169178)
Antigène
Voir toutes IL-37 (IL37) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
- Recognizes human IL-37. Detects a band of ~30 kDa by Western blot.
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Réactivité croisée
- Humain
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant human IL-37.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
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Agent conservateur
- Without preservative
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 6 months after receipt when stored at -20°C. -
Date de péremption
- 6 months
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- IL-37 (IL37) (Interleukin 37 (IL37))
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Autre désignation
- IL-37
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Sujet
- IL-37 (IL-1F7, IL-1H4) is an IL-1 family member that is expressed only in certain types of human organs and cells such as heart, thymus, testis, kidney, mononuclear cells (PBMCs) and dendritic cells. IL-37 is an inhibitor of innate immunity with anti-inflammatory properties. It binds to the interleukin-18 receptor (IL-18R) and its co-receptor SIGIRR. IL-37 is secreted as a full-length and as a processed form starting from amino acid Val46. It plays an important role as a link between innate and adaptive immunity and acts as an inhibitor of autoimmune diseases and tumor growth. IL-37 also inhibited Lipopolysaccharide (LPS)-induced immunological reaction and LPS-induced osteoclast formation and bone resorption.
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UniProt
- Q9NZH6
Antigène
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