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IDO1 anticorps

IDO1 Reactivité: Souris WB, ELISA, IHC, ICC Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN1169195
  • Antigène Voir toutes IDO1 Anticorps
    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
    Reactivité
    • 62
    • 30
    • 16
    • 8
    • 1
    • 1
    • 1
    Souris
    Hôte
    • 56
    • 11
    • 1
    • 1
    Lapin
    Clonalité
    • 55
    • 15
    Polyclonal
    Conjugué
    • 47
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp IDO1 est non-conjugé
    Application
    • 62
    • 31
    • 22
    • 19
    • 16
    • 15
    • 14
    • 8
    • 7
    • 5
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunocytochemistry (ICC)
    Specificité
    Recognizes mouse IDO. Detects a band of ~45 kDa by Western blot.
     Réactivité croisée
    Souris
    Stérilité
    0.2 μm filtered
    Immunogène
    Recombinant mouse IDO.
    Top Product
    Discover our top product IDO1 Anticorps primaire
  • Indications d'application
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.
    Agent conservateur
    Without preservative
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Short Term Storage: +4°C
    Long Term Storage: -20°C
    Stable for at least 6 months after receipt when stored at -20°C.
    Date de péremption
    6 months
  • Jung, Lee, Chang, Lee, Jeong, Lee, Park, Han, Seo, Lee, Park: "Blockade of indoleamine 2,3-dioxygenase protects mice against lipopolysaccharide-induced endotoxin shock." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 182, Issue 5, pp. 3146-54, (2009) (PubMed).

    Yen, Lin, Chen, Huang, Yang, Chang, Lei, Lai: "A novel cancer therapy by skin delivery of indoleamine 2,3-dioxygenase siRNA." dans: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 15, Issue 2, pp. 641-9, (2009) (PubMed).

    Cook, Bickerstaff, Wang, Nadasdy, Della Pelle, Colvin, Orosz: "Spontaneous renal allograft acceptance associated with "regulatory" dendritic cells and IDO." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 180, Issue 5, pp. 3103-12, (2008) (PubMed).

    Yadav, Burudi, Alirezaei, Flynn, Watry, Lanigan, Fox: "IFN-gamma-induced IDO and WRS expression in microglia is differentially regulated by IL-4." dans: Glia, Vol. 55, Issue 13, pp. 1385-96, (2007) (PubMed).

  • Antigène
    IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))
    Autre désignation
    IDO (IDO1 Produits)
    Synonymes
    anticorps INDO, anticorps ido, anticorps indo, anticorps IDO, anticorps cd107b, anticorps IDO1, anticorps IDO-1, anticorps Ido, anticorps Indo, anticorps indoleamine 2,3-dioxygenase 1, anticorps indoleamine 2,3-dioxygenase 1 L homeolog, anticorps indoleamine 2,3-dioxygenase 1-like, anticorps IDO1, anticorps ido1.L, anticorps ido1, anticorps Ido1, anticorps LOC100050681
    Sujet
    IDO catalyzes the first and rate-limiting step in the main pathway of human tryptophan catabolism, the kynurenine pathway. Proinflammatory mediators, such as endotoxin and IFN-gamma induce the expression of IDO in several tissues. IDO-dependent suppression of T-cell responses might function as natural immunoregulatory mechanism. Physiological IDO activity has been implicated in T-cell tolerance to tumors, dysfunctional selftolerance in non-obese diabetic (NOD) mice, and as a protective negative regulator in autoimmune disorders.
    UniProt
    P28776
    Pathways
    Activated T Cell Proliferation
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