NQO1 anticorps

N° du produit ABIN1169221

Cet anticorps Souris Monoclonal détecte spécifiquement NQO1 dans WB et ELISA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NQO1 anticorps (ABIN1169221)

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp NQO1 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: Skiny-1

Détail du produit anti-NQO1 anticorps

Fonction: anti-NQO1 (human), mAb (Skiny-1)

Specificité: Recognizes human NQO1. Detects a band of ~32 kDa by Western blot.

Attributs du produit: Monoclonal Antibody. Recognizes human NQO1. Detects a band of ~32 kDa by Western blot. Isotype: Mouse IgG2akappa. Clone: Skiny-1. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human NQO1.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.2μm-filtered solution in PBS, pH 7.4.

Agent conservateur: Without preservative

Conseil sur la manipulation: After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire:

+4°C

-20°C

Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur NQO1

Antigène: NQO1 (NAD(P)H Dehydrogenase, Quinone 1 (NQO1))

Autre désignation: NQO1

Sujet:

Alternate Names/Synonyms: NAD(P)H Dehydrogenase (Quinine) 1 (NQO1), Quinone Reductase 1 (QR1), DT-Diaphorase (DTD), Azoreductase, Phylloquinone Reductase, Menadione Reductase, Dioxin-inducible 1, Disphorase-4 (DIA4), NAD(P)H:Quinone Oxireductase, NAD(P)H:Quinone Oxidoreductase 1

Product Description: NQO1 is a cytosolic antioxidant flavoprotein that catalyzes the reduction of highly reactive quinone metabolites and their derivatives by using NAD(P)H as an electron donor. Thus NQO1 acts as a detoxyfying enzyme and is involved in the body's protection against oxidative stress. NQO1 acts as a protein chaperone, one of its targets being p53. In humans NQO1 is expressed at high levels in adipocytes and its expression levels are positively correlated with adiposity, glucose tolerance, and makers of liver dysfunction. Altered expression of NQO1 is associated with Alzheimer's disease. NQO1 is abnormally elevated in many types of solid tumors and may represent a useful biomarker of pancreatic cancer.

UniProt: Q3B792