Adiponectin Receptor 1 anticorps (AA 2-36)
Aperçu rapide pour Adiponectin Receptor 1 anticorps (AA 2-36) (ABIN1169254)
Antigène
Voir toutes Adiponectin Receptor 1 (ADIPOR1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 2-36
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Fonction
- anti-Adiponectin Receptor 1 (human), pAb (AL238)
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Specificité
- Recognizes human adiponectin receptor 1.
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Attributs du produit
- Polyclonal Antibody. Recognizes human adiponectin receptor 1. Source: Rabbit. Applications: IHC, WB. Liquid. Neat serum containing 0.02 % sodium azide. AdipoR1 is a receptor for globular and full-length adiponectin, an essential hormone secreted by adipocytes that acts as an antidiabetic. AdipoR1 is probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. It mediates increased AMPK, PPAR-alpha ligand activity, fatty acid oxidation and glucose uptake by adiponectin. It is a high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. It is widely expressed.
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Immunogène
- Synthetic peptide corresponding to aa 2-36 (S2SHKGSVVAQGNGAPASNREADTVELAEL GPLLEE36) of human adiponectin receptor 1.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Neat serum containing 0.02 % sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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Date de péremption
- 12 months
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: "Fibrosis is associated with adiponectin resistance in chronic hepatitis C virus infection." dans: European journal of clinical investigation, Vol. 41, Issue 8, pp. 898-905, (2011) (PubMed).
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- Adiponectin Receptor 1 (ADIPOR1)
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Autre désignation
- Adiponectin Receptor 1
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Sujet
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Alternate Names/Synonyms: AdipoR1, CGI-45
Product Description: AdipoR1 is a receptor for globular and full-length adiponectin, an essential hormone secreted by adipocytes that acts as an antidiabetic. AdipoR1 is probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. It mediates increased AMPK, PPAR-alpha ligand activity, fatty acid oxidation and glucose uptake by adiponectin. It is a high-affinity receptor for globular adiponectin but low-affinity receptor for full-length adiponectin. It is widely expressed.
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UniProt
- Q96A54
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Pathways
- AMPK Signaling
Antigène
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