CTRP6 anticorps (Globular Domain, Globular Domain-less)

N° du produit ABIN1169274

Cet anticorps anti-CTRP6 Monoclonal Souris (Clone 256-E) (ABIN1169274) détecte spécifiquement CTRP6 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour CTRP6 anticorps (Globular Domain, Globular Domain-less) (ABIN1169274)

Antigène: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTRP6 est non-conjugé

Application: Western Blotting (WB), ELISA

Clone: 256-E

Détail du produit anti-CTRP6 anticorps

Épitope: Globular Domain, Globular Domain-less

Specificité: Recognizes the N-terminal half of human CTRP6 full-length protein. Detects bands of ~16 kDa and ~32 kDa by Western blot.

Réactivité croisée: Humain

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human CTRP6 (globular domain-less).

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur CTRP6

Antigène: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Autre désignation: CTRP6

Sujet: CTRP6 mediates the phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in skeletal muscle cells, subsequently mediating glycogen accumulation and fatty acid oxidation. It induces the expression of the potent anti-inflammatory cytokine IL-10 in macrophages. CTRP6 may be a potential serum marker for hepatocellular carcinoma, contributing to tumor angiogenesis by activating the Akt pathway. CTRP6 was also shown to be associated with obesity, type 1 diabetes mellitus (T1D), vitiligo (depigmentation of the skin) and ASFV (African Swine Fever Virus). CTRP6 forms homotrimers and higher-order oligomers and it may also form heteromeric complexes with CTRP1. May be involved in kidney inflammation.

UniProt: Q9BXI9