CTRP6 anticorps (Globular Domain, Globular Domain-less)

N° du produit ABIN1169274

Détail du produit anti-CTRP6 anticorps

Antigène: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Épitope: Globular Domain, Globular Domain-less

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CTRP6 est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: Recognizes the N-terminal half of human CTRP6 full-length protein. Detects bands of ~16 kDa and ~32 kDa by Western blot.

Réactivité croisée: Humain

Purification: Purified from concentrated hybridoma tissue culture supernatant.

Stérilité: 0.2 μm filtered

Immunogène: Recombinant human CTRP6 (globular domain-less).

Clone: 256-E

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives.

Agent conservateur: Without preservative

Stock: 4 °C,-20 °C

Stockage commentaire: Short Term Storage: +4°C
Long Term Storage: -20°C
Stable for at least 1 year after receipt when stored at -20°C.

Date de péremption: 12 months

Détails sur CTRP6

Antigène: CTRP6 (C1QTNF6) (Complement C1q Tumor Necrosis Factor-Related Protein 6 (C1QTNF6))

Autre désignation: CTRP6 (C1QTNF6 Produits)

Synonymes: anticorps MGC148634, anticorps CTFP6, anticorps CTRP6, anticorps ZACRP6, anticorps 2810036M19Rik, anticorps Ctrp6, anticorps C1q and TNF related 6, anticorps C1q and tumor necrosis factor related protein 6, anticorps C1QTNF6, anticorps C1qtnf6

Sujet: CTRP6 mediates the phosphorylation of AMPK and acetyl-CoA carboxylase (ACC) in skeletal muscle cells, subsequently mediating glycogen accumulation and fatty acid oxidation. It induces the expression of the potent anti-inflammatory cytokine IL-10 in macrophages. CTRP6 may be a potential serum marker for hepatocellular carcinoma, contributing to tumor angiogenesis by activating the Akt pathway. CTRP6 was also shown to be associated with obesity, type 1 diabetes mellitus (T1D), vitiligo (depigmentation of the skin) and ASFV (African Swine Fever Virus). CTRP6 forms homotrimers and higher-order oligomers and it may also form heteromeric complexes with CTRP1. May be involved in kidney inflammation.

UniProt: Q9BXI9