Resistin anticorps
Aperçu rapide pour Resistin anticorps (ABIN1169370)
Antigène
Voir toutes Resistin (RETN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Fonction
- anti-Resistin (human), pAb
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Specificité
- Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10 kDa by Western blot.
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Réactivité croisée (Details)
- Weakly cross-reacts with mouse resistin.
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Attributs du produit
- Polyclonal Antibody. Recognizes human resistin. Weakly cross-reacts with mouse resistin. Detects a band of ~10 kDa by Western blot. Source: Rabbit. Applications: ELISA, WB. Liquid. 0.2μm-filtered solution in PBS, pH 7.4. Contains no preservatives. The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
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Stérilité
- 0.2 μm filtered
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Immunogène
- Recombinant human resistin.
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 1 mg/mL
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Buffer
- 0.2μm-filtered solution in PBS, pH 7.4.
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Agent conservateur
- Without preservative
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Conseil sur la manipulation
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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+4°C
-20°C
Stable for at least 6 months after receipt when stored at -20°C.
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Date de péremption
- 6 months
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: "Common genetic polymorphisms in the promoter of resistin gene are major determinants of plasma resistin concentrations in humans." dans: Diabetologia, Vol. 47, Issue 3, pp. 559-65, (2004) (PubMed).
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- Resistin (RETN)
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Autre désignation
- Resistin
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Sujet
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Alternate Names/Synonyms: FIZZ3, Found in Inflammatory Zone 3, ADSF, Adipose Tissue-Specific Secretory Factor
Product Description: The adipocytokine resistin which belongs to a family of cysteine-rich C-terminal proteins known as resistin-like molecules (RELM, RELMalpha/FIZZ 1 and RELMbeta/FIZZ 2) of FIZZ (found in inflammatory zone) are thought to be involved in inflammatory processes. Previous studies in mice showed that resistin impairs glucose tolerance and insulin action. In addition, resistin also inhibits adipogenesis in murine 3T3-L1 cells. Therefore resistin has also been proposed as an adipocyte-secreted factor thought to link obesity and T2DM.
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UniProt
- Q9HD89
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Pathways
- Feeding Behaviour, Smooth Muscle Cell Migration
Antigène
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