IL-10RA anticorps

N° du produit ABIN1177308

Détail du produit anti-IL-10RA anticorps

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Reactivité: Humain

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-10RA est non-conjugé

Application: Flow Cytometry (FACS)

Marque: BD Pharmingen™

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Stérilité: 0.2 μm filtered

niveau d'endotoxine: Endotoxin level is ≤ 0.01 EU/μg (≤ 0.001 ng/μg) of protein as determined by the LAL assay.

Clone: 3F9

Isotype: IgG2a kappa

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Buffer: No azide/low endotoxin: Aqueous buffered solution containing no preservative, 0.2μm sterile filtered.

Agent conservateur: Azide free

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C. This preparation contains no preservatives, thus it should be handled under aseptic conditions.

Références pour anticorps anti-IL-10RA (ABIN1177308)

Liu, de Waal Malefyt, Briere, Parham, Bridon, Banchereau, Moore, Xu: "The EBV IL-10 homologue is a selective agonist with impaired binding to the IL-10 receptor." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 158, Issue 2, pp. 604-13, (1997) (PubMed).

Carson, Lindemann, Baiocchi, Linett, Tan, Chou, Narula, Caligiuri: "The functional characterization of interleukin-10 receptor expression on human natural killer cells." dans: Blood, Vol. 85, Issue 12, pp. 3577-85, (1995) (PubMed).

Détails sur IL-10RA

Antigène: IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))

Autre désignation: CD210 (IL10RA Produits)

Synonymes: anticorps IL10R1, anticorps IL10RA, anticorps CD210, anticorps CD210a, anticorps CDW210A, anticorps HIL-10R, anticorps IL-10R1, anticorps IL10R, anticorps AW553859, anticorps CDw210, anticorps CDw210a, anticorps Il10r, anticorps mIL-10R, anticorps interleukin 10 receptor subunit alpha, anticorps interleukin 10 receptor, alpha, anticorps IL10RA, anticorps Il10ra

Sujet: Reacts with 90-110 kDa protein expressed on T cells, B cells, NK cells, and monocyte/macrophages. It belongs to the class II cytokine receptor family which includes IFNgammaR (CDw119), IFNalpha/betaR (CD118) and tissue factor (CD142). IL-10R has been found to play a role in signal transduction by activating specific STAT proteins (STAT3 and STAT1) and inducing gene transcription. Other reports indicate that IL-10 protein binding to NK cells appears to be stimulatory, in contrast to its binding to T cells and monocytes/macrophages. Clone 3F9 is specific for human IL-10R and its binding to the receptor can be blocked by recombinant human IL-10 (rhIL-10).
Synonyms: IL-10 receptor

Pathways: Growth Factor Binding