Phosphotyrosine anticorps

N° du produit ABIN1177365

Cité dans 3 publications. Cet anticorps anti-Phosphotyrosine Monoclonal Souris (Clone PY20) (ABIN1177365) détecte spécifiquement Phosphotyrosine dans ICS.

Aperçu rapide pour Phosphotyrosine anticorps (ABIN1177365)

Antigène: Phosphotyrosine

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Phosphotyrosine est non-conjugé

Application: Intracellular Staining (ICS)

Clone: PY20

Détail du produit anti-Phosphotyrosine anticorps

Marque: BD Phosflow™

Purification: Purified from tissue culture supernatant or ascites by affinity chromatography

Isotype: IgG2b

Information d'application

Volume d'échantillon: 20 μL

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Aqueous buffered solution containing BSA and ≤0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. The antibody was conjugated with R-PE under optimum conditions, and unconjugated antibody and free PE were removed.

Références pour anticorps anti-Phosphotyrosine (ABIN1177365)

Arvidsson, Rupp, Nånberg, Downward, Rönnstrand, Wennström, Schlessinger, Heldin, Claesson-Welsh: "Tyr-716 in the platelet-derived growth factor beta-receptor kinase insert is involved in GRB2 binding and Ras activation." dans: Molecular and cellular biology, Vol. 14, Issue 10, pp. 6715-26, (1994) (PubMed).

Fan, Mendelsohn, Masui, Kumar: "Regulation of epidermal growth factor receptor in NIH3T3/HER14 cells by antireceptor monoclonal antibodies." dans: The Journal of biological chemistry, Vol. 268, Issue 28, pp. 21073-9, (1993) (PubMed).

Glenney, Zokas, Kamps: "Monoclonal antibodies to phosphotyrosine." dans: Journal of immunological methods, Vol. 109, Issue 2, pp. 277-85, (1988) (PubMed).

Détails sur Phosphotyrosine

Antigène: Phosphotyrosine

Classe de substances: Amino Acid

Sujet: Phosphorylation of specific tyrosine residues is the result of activation or stimulation of their respective protein tyrosine kinases. The phosphorylated proteins can be autophosphorylated kinases or certain protein substrates that are regulated in oncogenesis or cell growth. Antibodies to phosphotyrosine provide one of the best tools for the detection and characterization of phosphotyrosine proteins.