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ZNF148 anticorps

ZNF148 Reactivité: Humain WB, EIA Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN117932
  • Antigène Voir toutes ZNF148 Anticorps
    ZNF148 (Zinc Finger Protein 148 (ZNF148))
    Reactivité
    • 43
    • 21
    • 19
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 43
    • 1
    Lapin
    Clonalité
    • 44
    Polyclonal
    Conjugué
    • 27
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ZNF148 est non-conjugé
    Application
    • 36
    • 19
    • 12
    • 9
    • 4
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Séquence
    1 mniddklegl flkcggidem qssrtmvvmg gvsgqstvsg elqdsvlqdr smphqeilaa 61 devlqesemr qqdmishdel mvheetvknd eeqmetherl pqglqyalnv pisvkqeitf 121 tdvseqlmrd kkqirepvdl qkkkkrkqrs pakiltined gslglktpks hvcehcnaaf 181 rtnyhlqrhv fihtgekpfq csqcdmrfiq kyllqrheki htgekpfrcd ecgmrfiqky 241 hmerhkrths gekpyqceyc lqyfsrtdrv lkhkrmchen hdkklntcai kgglltseed 301 sgfstspkdn slpkkkrqkt ekkssgmdke saldksdlkk dkndylpvys sstkvkdeym 361 vaeyavemph ssvggshled asgeihppkl vlkkinskrs lkqpleqnqt isplstyees 421 kvskyafelv dkqalldseg nadidqvdnl qegpskpvhs stnyddamqf lkkkrylqaa 481 snnsreyaln vgtirsqpsv tqaavasvid esttasiles qalnveiksn hdknvipdev 541 lqtlldhysh kangqheisf svadtevtss isinssevpe vtpsenvgss sqasssdkan 601 mlqeyskflq qaldrtsqnd aylnspslnf vtdnqtlpnq pafssidkqv yatmpinsfr 661 sgmnsplrtt pdkshfgliv gdsqhsfpfs gdetnhasat stqdfldqvt sqkkaeaqpv 721 hqayqmssfe qpfrapyhgs ragiatqfst angqvnlrgp gtsaefsefp lvnvndnrag 781 mtsspdattg qtfg
    Specificité
    This polyclonal antibody is specific for ZBP-89.
    Purification
    Delipidation and defibrination
    Immunogène
    Purified full length ZBP-89 recombinant protein expressed in E.coli
    Top Product
    Discover our top product ZNF148 Anticorps primaire
  • Indications d'application
    This polyclonal antibody reacts human ZBP-89 in a variety of immunological assaysincluding western blot and ELISA. This antibody is likely functional inimmunohistochemistry and immunoprecipitation. Recommended dilutionsImmunoblotting: 1: 5,000. A band at approximately 89 kDa corresponding to human ZBP-89is detected. Human monocytes or macrophages or nuclear extracts from PMA treated U937cells can be used as a positive control. ELISA: 1: 10,000 - 1: 30,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    90 mg/mL (by Refractometry)
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
  • Antigène
    ZNF148 (Zinc Finger Protein 148 (ZNF148))
    Autre désignation
    ZNF148 (ZNF148 Produits)
    Synonymes
    anticorps BERF-1, anticorps BFCOL1, anticorps HT-BETA, anticorps ZBP-89, anticorps ZFP148, anticorps pHZ-52, anticorps 2210405J08Rik, anticorps AI480666, anticorps AW045217, anticorps Znf148, anticorps Zbp-89, anticorps fb06h05, anticorps wu:fb06h05, anticorps zfp149, anticorps zgc:165342, anticorps SLC12A8, anticorps zinc finger protein 148, anticorps ZNF148, anticorps Zfp148, anticorps znf148
    Sujet
    The GI tract abundantly expresses growth factors many of which bind and activate the EGF receptor present on mucosal cells. One such factor is the zinc finger protein (ZBP-89) that binds to a GC-rich DNA element in the gastrin promoter and confers EGF responsiveness. The fulllength protein functions as a repressor of growth factor signals regulating the gastrin promoter. Several other growth related promoters are also regulated by ZBP-89. ZBP-89 is one of a family of related transcriptional regulators. It has been reported in recent studies that ZBP-89 regulates growth in part by stimulating the cyclin-dependent kinase inhibitor, p21waf1, in a butyrate-dependent manner through recruitment of the histone acetyl transferase p300. Moreover, ZBP-89 triggers growth arrest in a p53-dependent manner by preventing nuclear export of p53. ZBP-89 also induces apoptosis, but this process occurs independent of p53.Synonyms: Transcription factor ZBP-89, ZBP89, Zinc finger DNA-binding protein 89, Zinc finger protein 148
    ID gène
    7707
    NCBI Accession
    NP_068799
    UniProt
    Q9UQR1
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