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ANAPC11 anticorps (C-Term)

ANAPC11 Reactivité: Humain WB, EIA, IP Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN117941
  • Antigène Voir toutes ANAPC11 Anticorps
    ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))
    Épitope
    • 16
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 76-84, C-Term
    Reactivité
    • 38
    • 3
    • 3
    Humain
    Hôte
    • 22
    • 15
    • 1
    Lapin
    Clonalité
    • 23
    • 15
    Polyclonal
    Conjugué
    • 17
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp ANAPC11 est non-conjugé
    Application
    • 31
    • 13
    • 13
    • 13
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunoprecipitation (IP)
    Séquence
    Human APC11 (84 aa 9.8 kDa): 1 mkvkikcwng vatwlwvand encgicrmaf ngccpdckvp gddcplvwgq cshcfhmhci 61 lkwlhaqqvq qhcpmcrqew kfke
    Specificité
    This product is monospecific antiserum processed by delipidation and defibrination followed by sterile filtration. This antibody reacts with human and mouse APC11. Cross reactivity may also occur with APC11 from other sources. Sufficient sequence differences exist to suggest that this antibody would not react with other RING box proteins such as ROC1 and ROC2.
    Purification
    Delipidation and defibrination.
    Immunogène
    This APC11 antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to amino acids 76-84 of Human APC11 (C-terminal) coupled to KLH.
    Top Product
    Discover our top product ANAPC11 Anticorps primaire
  • Indications d'application
    Western blot (1: 500-1: 1,000). ELISA (1: 2,000-1: 10,000). Immunoprecipitation: The antibody immunoprecipitates in vitro translated protein andprotein from overexpressing cell lysates (using HeLa and NIH-3T3, and others). Coimmunoprecipitation of related proteins (APC2) does occur. A 9.8 kDa bandcorresponding to human APC11 is detected. Most cell lines or tissues expressing APC11 canbe used as a positive control.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    85 mg/mL (by Refractometry)
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -80 °C for longer.
  • Antigène
    ANAPC11 (Anaphase Promoting Complex Subunit 11 (ANAPC11))
    Autre désignation
    APC11 / ANAPC11 (ANAPC11 Produits)
    Synonymes
    anticorps APC11, anticorps Apc11p, anticorps anapc11, anticorps RGD1561880, anticorps F10A16.17, anticorps F10A16_17, anticorps anaphase-promoting complex/cyclosome 11, anticorps DDBDRAFT_0187183, anticorps DDBDRAFT_0231277, anticorps DDB_0187183, anticorps DDB_0231277, anticorps 1110011I19Rik, anticorps R75218, anticorps zgc:153671, anticorps si:dkey-237i9.4, anticorps anaphase promoting complex subunit 11, anticorps anaphase promoting complex subunit 11 L homeolog, anticorps anaphase-promoting complex/cyclosome 11, anticorps anaphase-promoting complex subunit Apc11, anticorps ubiquitin-protein ligase Anaphase Promoting Complex, anticorps hypothetical protein, anticorps predicted protein, anticorps anaphase-promoting complex subunit 11, anticorps APC11 anaphase promoting complex subunit 11 homolog (yeast), anticorps ANAPC11, anticorps anapc11.L, anticorps anapc11, anticorps Anapc11, anticorps APC11, anticorps apc11, anticorps CAALFM_CR10610CA, anticorps LOC9320604, anticorps LOC692923
    Sujet
    APC11 is also known as Anaphase promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma associated RING finger protein, and HSPC214. APC11 is a component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC11 may function to recruit the E2 ubiquitin-conjugating enzymes to the complex. APC11 interacts with the cullin domain of ANAPC2 and also interacts with UBE2D2. APC11 shows both a cytoplasmic and nuclear localization. APC11 is expressed at high levels in skeletal muscle and heart, in moderate levels in brain, kidney, and liver, and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte. APC11 is a member of the RING-type zinc finger family and is auto-ubiquitinylated.Synonyms: Anaphase-promoting complex subunit 11, Cyclosome subunit 11, HSPC214, Hepatocellular carcinoma-associated RING finger protein
    ID gène
    51529
    NCBI Accession
    NP_001002244
    UniProt
    Q9NYG5
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