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CD8 anticorps (FITC)

Cet anticorps Rat Monoclonal détecte spécifiquement CD8 dans FACS. Il présente une réactivité envers Souris.
N° du produit ABIN118129

Aperçu rapide pour CD8 anticorps (FITC) (ABIN118129)

Antigène

Voir toutes CD8 Anticorps
CD8

Reactivité

  • 205
  • 65
  • 25
  • 12
  • 12
  • 12
  • 9
  • 9
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  • 8
  • 6
  • 6
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  • 3
  • 2
  • 1
  • 1
Souris

Hôte

  • 241
  • 48
  • 33
  • 4
Rat

Clonalité

  • 290
  • 29
  • 2
Monoclonal

Conjugué

  • 100
  • 50
  • 38
  • 25
  • 14
  • 7
  • 5
  • 5
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  • 5
  • 5
  • 3
  • 3
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  • 2
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  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
Cet anticorp CD8 est conjugé à/à la FITC

Application

  • 286
  • 65
  • 53
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  • 50
  • 46
  • 28
  • 18
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  • 16
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  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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  • 1
Flow Cytometry (FACS)

Clone

KT15
  • Specificité

    This antibody reacts with a non-polymorphic epitope on the CD8 alpha chain. Stains mouse Ly2.1 and Ly2.2 cells.

    Purification

    Affinity chromatography on Protein A

    Immunogène

    T cell clone, C6. Spleen cells from immunised SD rats were fused with cells of the NSO mouse myeloma cell line.

    Isotype

    IgG2a
  • Indications d'application

    Flow cytometry: Neat - 1/10, use 10 μL of the suggested working dilution to label 10^6 cellsin 100 μL, The Fc region of monoclonal antibodies may bind non-specifically to cellsexpressing low affinity Fc receptors.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.

    Restrictions

    For Research Use only
  • Concentration

    0.1 mg/mL

    Buffer

    PBS, pH 7.4 containing 0.09 % Sodium Azide and 1 % Bovine Serum Albumin

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing. Shelf live: one year from despatch.

    Stock

    4 °C/-20 °C

    Stockage commentaire

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Antigène

    CD8

    Autre désignation

    CD8

    Sujet

    The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2

    ID gène

    12525

    NCBI Accession

    NP_001074579

    UniProt

    P01731
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