CD8 anticorps (PE)
Aperçu rapide pour CD8 anticorps (PE) (ABIN118134)
Antigène
Voir toutes CD8 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody reacts to Ly2.1 and Ly2.2 cells. Reacts with the CD8 alpha chain (non polymorphic). Weakly cytotoxic.
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Immunogène
- T cell clone, C6. Spleen cells from a Spraque Dawley rat immunised with the C6 T cell clone were fused with cells of the NSO mouse myeloma cell line.
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Isotype
- IgG2a
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Indications d'application
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Flow Cytometry: Use 10 μL of Neat-1/10 diluted antibody to label 10^6 cells in 100 μL. The Fc region of monoclonal antibodies may bind non-specifically to cells expressing low affinity Fc receptors.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with distilled water: SM011R with 1.0 mL SM011RT with 0.25 mL SM011RX with 5.0 ml
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Buffer
- PBS containing 0.09 % Sodium Azide as presrevative and 1 % BSA as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- This product is photosensitive and should be protected from light
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Stock
- 4 °C
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Stockage commentaire
- Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
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- CD8
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Autre désignation
- CD8
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Sujet
- The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains.Synonyms: CD8 alpha chain, CD8A, MAL, T-cell surface glycoprotein CD8 alpha chain, T-lymphocyte differentiation antigen T8/Leu-2
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ID gène
- 12525
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NCBI Accession
- NP_001074579
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UniProt
- P01731
Antigène
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