CD7 anticorps (Biotin)

N° du produit ABIN118543

Cet anticorps Souris Monoclonal détecte spécifiquement CD7 dans FACS et IHC (fro). Il présente une réactivité envers Humain.

Aperçu rapide pour CD7 anticorps (Biotin) (ABIN118543)

Antigène: CD7

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD7 est conjugé à/à la Biotin

Application: Flow Cytometry (FACS), Immunohistochemistry (Frozen Sections) (IHC (fro))

Clone: LT7

Détail du produit anti-CD7 anticorps (Biotin)

Specificité: This antibody is a single chain cell surface glycoprotein of 40 kDa, expressed by T cells, NK cells and thymocytes. CD7 is also expressed by tumour cells in some cases of acute myeloid leukaemia.

Purification: Affinity chromatography on Protein A

Immunogène: Normal human peripheral blood lymphocytes. Spleen cells from immunised BALB/c mice were fused with cells of the X63.653 mouse myeloma cell line.

Isotype: IgG2a

Information d'application

Indications d'application: Flow Cytometry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.1 mg/mL

Buffer: PBS, pH 7.4 containing 0.09 % Sodium Azide as preservative and 1 % Bovine Serum Albumin as stabilizer.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur CD7

Antigène: CD7

Autre désignation: CD7

Sujet: CD7 is a 40 kDa transmembrane, single-chain glycoprotein, which is a member of the immunoglobulin superfamily. CD7 is expressed by the majority of thymocytes and mature T cells, NK cells and pre-B cells. It plays an essential role in T-cell interactions and also in T-cell/B-cell interaction during early lymphoid development. The function of CD7 is not yet known although cross-linking of CD7 with antibodies induces a T cell transmembrane calcium flux and CD7 expression is induced by ionomycin. The CD7 Molecule has been reported to be the receptor for the IgM-Fc portion (FcR mu) on the surface of T cells.Synonyms: GP40, Leu-9, T-cell leukemia antigen, TP41

ID gène: 924

NCBI Accession: NP_006128

UniProt: P09564

Pathways: Cell-Cell Junction Organization