Endoglin anticorps (PE)
Aperçu rapide pour Endoglin anticorps (PE) (ABIN118833)
Antigène
Voir toutes Endoglin (ENG) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
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Specificité
- This antibody recognises the human CD105 cell surface antigen, a glycoprotein homodimer of 95 kDa subunits.
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Purification
- Affinity Chromatography on Protein G.
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Immunogène
- Partially purified cell membrane antigens from fresh leukaemia cells
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Isotype
- IgG1
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Indications d'application
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Flow cytometry: Use 10 μL of neat antibody to label 10^6 cells in 100 μL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Reconstitution
- Restore with 1.0 mL distilled water.
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Buffer
- PBS, pH 7.4, containing 0.09 % sodium azide as preservative and 1 % BSA as stabilizer.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- This product is photosensitive and should be protected from light
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Stock
- 4 °C
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Stockage commentaire
- Prior to and following reconstitution store the antibody at 2-8 °C. DO NOT FREEZE!
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- Endoglin (ENG)
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Autre désignation
- CD105 / Endoglin
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Sujet
- CD105 or Endoglin is a Type I transmembrane protein, which is highly expressed on human vascular endothelial cells. It exists on an O- and N-glycosylated homodimer. Up regulation of endoglin expression has been demonstrated in tumor vasculature and proliferating cells, suggesting that it is a proliferation associated endothelial marker. CD105 binds to TGF beta 1 and 3 with high affinity but not to TGF beta 2.Synonyms: END, ENG, HHT1, ORW, ORW1
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ID gène
- 9606
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UniProt
- P17813
Antigène
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