FCAR anticorps

N° du produit ABIN118855

Cet anticorps Souris Monoclonal détecte spécifiquement FCAR dans WB, FACS, IP et EIA. Il présente une réactivité envers Humain.

Aperçu rapide pour FCAR anticorps (ABIN118855)

Antigène: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp FCAR est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA)

Clone: MIP8a

Détail du produit anti-FCAR anticorps

Specificité: This antibody recognises the CD89 cell surface antigen. Clone MIP8a blocks binding of IgA to the Fc alpha R, and also inhibits neutrophil phagocytosis of IgA complexes. The preservative free format of this antibody (product code SM1198A) is recommended for functional studies.

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Purified

Immunogène: Recombinant soluble Human Fc alpha R

Isotype: IgG1

Information d'application

Indications d'application: Flow Cytometry: Use 10 μL of 1/50-1/100 diluted antibody to label 10^6 cells or 100 μL whole blood. ELISA. Immunoprecipitation. Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur FCAR

Antigène: FCAR (Fc Fragment of IgA, Receptor For (FCAR))

Autre désignation: CD89 / FCAR

Sujet: CD89 cell surface antigen is a 50-70kD glycoprotein that is also known as the IgA receptor. CD89 is expressed by peripheral blood neutrophils and monocytes. Human CD89 is present on a number of cell types, including neutrophils, monocytes, macrophages, and eosinophils. FCAR interacts with aggregated IgAs, such as IgA coated on the surface of an invading microorganism, and mediates several immunologic defense processes such as phagocytosis, antibody dependent cell mediated cytotoxicity, and stimulation of the release of inflammatory mediators. FCAR is a glycoprotein of 50 to 100 kD, with diversity on different cell types.Synonyms: IgA Fc receptor, Immunoglobulin alpha Fc receptor

ID gène: 2204

NCBI Accession: NP_001991

UniProt: P24071